The mycobiome in health and disease: emerging concepts, methodologies and challenges

PY Tiew, M Mac Aogain, NABM Ali, KX Thng, K Goh… - Mycopathologia, 2020 - Springer
Fungal disease is an increasingly recognised global clinical challenge associated with high
mortality. Early diagnosis of fungal infection remains problematic due to the poor sensitivity …

The global challenge of carbapenem-resistant Enterobacteriaceae in transplant recipients and patients with hematologic malignancies

MJ Satlin, SG Jenkins, TJ Walsh - Clinical infectious diseases, 2014 - academic.oup.com
Carbapenem-resistant Enterobacteriaceae (CRE) are emerging global pathogens. The
spread of CRE to transplant recipients and patients with hematologic malignancies has …

FDA-ARGOS is a database with public quality-controlled reference genomes for diagnostic use and regulatory science

H Sichtig, T Minogue, Y Yan, C Stefan, A Hall… - Nature …, 2019 - nature.com
FDA proactively invests in tools to support innovation of emerging technologies, such as
infectious disease next generation sequencing (ID-NGS). Here, we introduce FDA-ARGOS …

Genomic medicine: a decade of successes, challenges, and opportunities

JJ McCarthy, HL McLeod, GS Ginsburg - Science translational …, 2013 - science.org
Genomic medicine—an aspirational term 10 years ago—is gaining momentum across the
entire clinical continuum from risk assessment in healthy individuals to genome-guided …

Genomic and transcriptomic analyses of colistin-resistant clinical isolates of Klebsiella pneumoniae reveal multiple pathways of resistance

MS Wright, Y Suzuki, MB Jones… - Antimicrobial agents …, 2015 - Am Soc Microbiol
The emergence of multidrug-resistant (MDR) Klebsiella pneumoniae has resulted in a more
frequent reliance on treatment using colistin. However, resistance to colistin (Colr) is …

Compositions and methods

G McKenzie, MJL McKenzie, DN Cook, M Vulic… - US Patent …, 2015 - Google Patents
US9180147B2 - Compositions and methods - Google Patents US9180147B2 - Compositions
and methods - Google Patents Compositions and methods Download PDF Info Publication …

Diversity, virulence, and antimicrobial resistance of the KPC-producing Klebsiella pneumoniae ST307 clone

L Villa, C Feudi, D Fortini, S Brisse… - Microbial …, 2017 - microbiologyresearch.org
The global spread of Klebsiella pneumoniae producing Klebsiella pneumoniae
carbapenemase (KPC) has been mainly associated with the dissemination of high-risk …

PathoScope 2.0: a complete computational framework for strain identification in environmental or clinical sequencing samples

C Hong, S Manimaran, Y Shen, JF Perez-Rogers… - Microbiome, 2014 - Springer
Background Recent innovations in sequencing technologies have provided researchers
with the ability to rapidly characterize the microbial content of an environmental or clinical …

[HTML][HTML] Carbapenem-resistant Enterobacteriaceae: a menace to our most vulnerable patients

F Perez, D Van Duin - Cleveland Clinic journal of medicine, 2013 - ncbi.nlm.nih.gov
The emergence of carbapenem-resistant Enterobacteriaceae (CRE) highlights the
importance of effective antibiotics to maintain the safety of our health care system. Clinicians …

Synergistic bacterial compositions and methods of production and use thereof

MR Henn, G Von Maltzahn, AM D'onofrio… - US Patent …, 2017 - Google Patents
Mammals are colonized by microbes in the gastrointes tinal (GI) tract, on the skin, and in
other epithelial and tissue niches Such as the oral cavity, eye surface and vagina. The …