Inhibition of fibrinolysis by lipoprotein (a)

E ANGLÉS‐CANO, ADLP Díaz… - Annals of the New York …, 2001 - Wiley Online Library
A high plasma concentration of lipoprotein Lp (a) is now considered to be a major and
independent risk factor for cerebro‐and cardiovascular atherothrombosis. The mechanism …

Lipoprotein Lp (a) and atherothrombotic disease

A de la Peña-Dı́az, R Izaguirre-Avila… - Archives of medical …, 2000 - Elsevier
High plasma concentrations of lipoprotein (a)[Lp (a)] are now considered a major risk factor
for atherosclerosis and cardiovascular disease. This effect of Lp (a) may be related to its …

[PDF][PDF] The Apo (a) gene is the major determinant of variation in plasma Lp (a) levels in African Americans

V Mooser, D Scheer, SM Marcovina, J Wang… - The American Journal of …, 1997 - cell.com
The distributions of plasma lipoprotein (a), or Lp (a), levels differ significantly among ethnic
groups. Individuals of African descent have a two-to threefold higher mean plasma level of …

Molecular basis of congenital lp (a) deficiency: a frequent apo (a)'null'mutation in caucasians

M Ogorelkova, A Gruber… - Human molecular …, 1999 - academic.oup.com
High plasma concentrations of lipoprotein (a)[Lp (a)], a covalent low-density lipoprotein-
apolipoprotein (a)[apo (a)] complex, are associated with coronary heart disease and stroke …

The metabolism of lipoprotein (a) and other apolipoprotein B-containing lipoproteins: a kinetic study in humans

T Demant, K Seeberg, A Bedynek, D Seidel - Atherosclerosis, 2001 - Elsevier
Lipoprotein (a) is a risk factor for cardiovascular disease composed of an apolipoprotein B-
containing lipoprotein to which a second protein, apolipoprotein (a), is attached. We …

Plasma lipoprotein (a) levels and expression of the apolipoprotein (a) gene are dependent on the nucleotide polymorphisms in its 5'-flanking region.

K Suzuki, M Kuriyama, T Saito… - The Journal of clinical …, 1997 - Am Soc Clin Investig
The apolipoprotein (a)(apo [a]) gene encodes a protein component of lipoprotein (a)[Lp (a)]
whose plasma levels vary widely among individuals. Hyper-Lp (a)-emia constitutes a risk …

LPA and PLG Sequence Variation and Kringle IV-2 Copy Number in Two Populations

DC Crawford, Z Peng, JF Cheng, D Boffelli, M Ahearn… - Human …, 2008 - karger.com
Abstract Background/Aims: Lp (a) levels have long been recognized as a potential risk factor
for coronary heart disease that is almost completely under genetic control. Much of the …

The apolipoprotein E4 allele is not associated with an abnormal lipid profile in a Native American population following its traditional lifestyle

CA Aguilar, G Talavera, JM Ordovas, JA Barriguete… - Atherosclerosis, 1999 - Elsevier
The apolipoprotein E4 allele is associated in industrialized countries with an elevated LDL
cholesterol concentration and an increased cardiovascular risk. Our purpose in this study …

Genetic factors play an important role in the pathogenesis of hyperlipidemia post-transplantation

CA Aguilar-Salinas, A Díaz-Polanco, E Quintana… - American journal of …, 2002 - Elsevier
Background: Our purpose was to identify factors associated with hyperlipidemia post-
transplantation in a Hispanic population. Methods: From 1985 to 1999, a kidney graft …

The relative electrophoretic mobility of apo (a) isoforms depends on the gel system: proposal of a nomenclature for apo (a) phenotypes

HG Kraft, A Lingenhel, G Bader, GM Kostner… - Atherosclerosis, 1996 - Elsevier
Genetic apo (a) isoforms were originally defined according to their relative mobility in SDS-
PAGE compared to apoB-100 and were designated as F, B or S1–S4 isotypes. This widely …