Many cancer patients suffer from severe fatigue when treated with chemotherapy or
radiotherapy; however, the etiology and pathogenesis of this kind of fatigue remains …

Cancer cachexia is a multi-factorial syndrome, which negatively affects quality of life,
responsiveness to chemotherapy, and survival in advanced cancer patients. Our …

Chronic diseases often lead to metabolic disorders, causing anabolic resistance and
increased energy consumption, which result in cachexia. Cachexia, in turn, can lead to …

Research investigators have shown a growing interest in investigating alterations underlying
skeletal muscle wasting in patients with cancer. However, skeletal muscle dysfunctions …

Objective This study aimed to provide evidence-based results on differences in overall
survival (OS) rate to guide the diagnosis of cancer cachexia. Design Data collection and …

Background Cachexia is a multi-factorial, systemic syndrome that especially affects patients
with cancer of the gastrointestinal tract, and leads to reduced treatment response, survival …

Obesity causes dysfunction of adipose tissue, with resultant chronic inflammation and
adverse interplay of various adipokines, sex steroids and endocrine hormones. All these …

The development of the syndrome of cancer cachexia and that of metastasis are related with
a poor prognostic for cancer patients. They are considered multifactorial processes …

Abstract Background In the COMFORT (COntrolled MyeloFibrosis Study with ORal JAK
Inhibitor Therapy)-I study, the Janus kinase (JAK) 1/JAK2 inhibitor ruxolitinib provided …

Lung cancer is the most common cause of cancer-related deaths. Lung cancers can be
classified as small-cell (SCLC) or non-small cell (NSCLC). About 84% of all lung cancers …