Radiation resistance: a matter of transcription factors

C Galeaz, C Totis, A Bisio - Frontiers in oncology, 2021 - frontiersin.org
Currently, radiation therapy is one of the standard therapies for cancer treatment. Since the
first applications, the field of radiotherapy has constantly improved, both in imaging …

[PDF][PDF] Prostaglandin pathways: opportunities for cancer prevention and therapy

Q Wang, RJ Morris, AM Bode, T Zhang - Cancer research, 2022 - AACR
Because of profound effects observed in carcinogenesis, prostaglandins (PGs),
prostaglandin-endoperoxide synthases, and PG receptors are implicated in cancer …

Fluorogenic reaction-based prodrug conjugates as targeted cancer theranostics

MH Lee, A Sharma, MJ Chang, J Lee, S Son… - Chemical Society …, 2018 - pubs.rsc.org
Theranostic systems are receiving ever-increasing attention due to their potential
therapeutic utility, imaging enhancement capability, and promise for advancing the field of …

The anticancer properties of Salvia miltiorrhiza Bunge (Danshen): a systematic review

X Chen, J Guo, J Bao, J Lu… - Medicinal research …, 2014 - Wiley Online Library
Abstract Salvia miltiorrhiza Bunge (Danshen in Chinese) is a classical Huoxue Huayu (a
traditional Chinese medical term means promoting blood circulation and removing blood …

Advances in the pharmacological activities and mechanisms of diosgenin

C Yan, T You-Mei, YU Su-Lan, HAN Yu-Wei… - Chinese journal of …, 2015 - Elsevier
Diosgenin, a well-known steroid sapogenin derived from plants, has been used as a starting
material for production of steroidal hormones. The present review will summarize published …

The wound healing, chronic fibrosis, and cancer progression triad

B Rybinski, J Franco-Barraza… - Physiological …, 2014 - journals.physiology.org
For decades tumors have been recognized as “wounds that do not heal.” Besides the
commonalities that tumors and wounded tissues share, the process of wound healing also …

Macrophages induce EMT to promote invasion of lung cancer cells through the IL-6-mediated COX-2/PGE2/β-catenin signalling pathway

D Che, S Zhang, Z Jing, L Shang, S Jin, F Liu… - Molecular …, 2017 - Elsevier
Infiltration of macrophages plays a critical role in the connection between inflammation and
cancer invasion; however, the molecular mechanism that enables this crosstalk remains …

Has the time come for metronomics in low-income and middle-income countries?

N André, S Banavali, Y Snihur, E Pasquier - The Lancet Oncology, 2013 - thelancet.com
Summary In 2008, 72% of cancer deaths occurred in low-income and middle-income
countries, where, although there is a lower incidence of cancer than in high-income …

Theranostic designs of biomaterials for precision medicine in cancer therapy

H Kim, G Kwak, K Kim, HY Yoon, IC Kwon - Biomaterials, 2019 - Elsevier
Theranostic biomaterials have been creating great new opportunities in developing
precision medicine in cancer treatment. Moreover, there exist up-coming potentials to find a …

Antagonizing STAT3 dimerization with a rhodium (III) complex

DL Ma, LJ Liu, KH Leung, YT Chen… - Angewandte …, 2014 - Wiley Online Library
Kinetically inert metal complexes have arisen as promising alternatives to existing platinum
and ruthenium chemotherapeutics. Reported herein, to our knowledge, is the first example …