Biomass-based biorefineries: an important architype towards a circular economy

B Kumar, P Verma - Fuel, 2021 - Elsevier
Fossil based resources are a major contributor to energy and chemicals to modern-day
development. The negative environmental impacts of fossil-based resources accompanied …

[HTML][HTML] Emerging technologies in algal biotechnology: toward the establishment of a sustainable, algae-based bioeconomy

M Fabris, RM Abbriano, M Pernice… - Frontiers in plant …, 2020 - frontiersin.org
Mankind has recognized the value of land plants as renewable sources of food, medicine,
and materials for millennia. Throughout human history, agricultural methods were …

Terpenes and isoprenoids: a wealth of compounds for global use

SD Tetali - Planta, 2019 - Springer
Main conclusion Role of terpenes and isoprenoids has been pivotal in the survival and
evolution of higher plants in various ecoregions. These products find application in the …

Engineering peroxisomal biosynthetic pathways for maximization of triterpene production in Yarrowia lipolytica

Y Ma, Y Shang… - Proceedings of the …, 2024 - National Acad Sciences
Constructing efficient cell factories for product synthesis is frequently hampered by
competing pathways and/or insufficient precursor supply. This is particularly evident in the …

Tailoring the Saccharomyces cerevisiae endoplasmic reticulum for functional assembly of terpene synthesis pathway

JE Kim, IS Jang, SH Son, YJ Ko, BK Cho, SC Kim… - Metabolic …, 2019 - Elsevier
The endoplasmic reticulum (ER) is a dynamic organelle that synthesizes and folds proteins.
An imbalance between the ER protein synthesis load and its folding capacity triggers the …

Enhancing isoprenoid synthesis in Yarrowia lipolytica by expressing the isopentenol utilization pathway and modulating intracellular hydrophobicity

Z Luo, N Liu, Z Lazar, A Chatzivasileiou, V Ward… - Metabolic …, 2020 - Elsevier
The abundant supply of biosynthetic precursors and product compatibility with the
intracellular environment play important roles for microbial isoprenoid production. In this …

[HTML][HTML] Enzymes revolutionize the bioproduction of value-added compounds: From enzyme discovery to special applications

B Wiltschi, T Cernava, A Dennig, MG Casas… - Biotechnology …, 2020 - Elsevier
Competitive sustainable production in industry demands new and better biocatalysts,
optimized bioprocesses and cost-effective product recovery. Our review sheds light on the …

[HTML][HTML] Identifying and engineering the ideal microbial terpenoid production host

S Moser, H Pichler - Applied Microbiology and Biotechnology, 2019 - Springer
More than 70,000 different terpenoid structures are known so far; many of them offer highly
interesting applications as pharmaceuticals, flavors and fragrances, or biofuels. Extraction of …

Global metabolic rewiring of the nonconventional yeast Ogataea polymorpha for biosynthesis of the sesquiterpenoid β-elemene

M Ye, J Gao, YJ Zhou - Metabolic engineering, 2023 - Elsevier
Bioproduction of natural products via microbial cell factories is a promising alternative to
traditional plant extraction. Recently, nonconventional microorganisms have emerged as …

The isoprenoid alcohol pathway, a synthetic route for isoprenoid biosynthesis

JM Clomburg, S Qian, Z Tan… - Proceedings of the …, 2019 - National Acad Sciences
The more than 50,000 isoprenoids found in nature are all derived from the 5-carbon
diphosphates isopentenyl pyrophosphate (IPP) and dimethylallyl pyrophosphate (DMAPP) …