[PDF][PDF] Angiogenesis and vascular functions in modulation of obesity, adipose metabolism, and insulin sensitivity
Y Cao - Cell metabolism, 2013 - cell.com
White and brown adipose tissues are hypervascularized and the adipose vasculature
displays phenotypic and functional plasticity to coordinate with metabolic demands of …
displays phenotypic and functional plasticity to coordinate with metabolic demands of …
The role of the islet niche on beta cell structure and function
The islets of Langerhans or pancreatic islets are pivotal in the control of blood glucose and
are complex microorgans embedded within the larger volume of the exocrine pancreas …
are complex microorgans embedded within the larger volume of the exocrine pancreas …
[PDF][PDF] Endogenous reprogramming of alpha cells into beta cells, induced by viral gene therapy, reverses autoimmune diabetes
X Xiao, P Guo, C Shiota, T Zhang, GM Coudriet… - Cell stem cell, 2018 - cell.com
Successful strategies for treating type 1 diabetes need to restore the function of pancreatic
beta cells that are destroyed by the immune system and overcome further destruction of …
beta cells that are destroyed by the immune system and overcome further destruction of …
M2 macrophages promote beta-cell proliferation by up-regulation of SMAD7
X Xiao, I Gaffar, P Guo, J Wiersch… - Proceedings of the …, 2014 - National Acad Sciences
Determination of signaling pathways that regulate beta-cell replication is critical for beta-cell
therapy. Here, we show that blocking pancreatic macrophage infiltration after pancreatic …
therapy. Here, we show that blocking pancreatic macrophage infiltration after pancreatic …
[HTML][HTML] No evidence for β cell neogenesis in murine adult pancreas
X Xiao, Z Chen, C Shiota, K Prasadan… - The Journal of …, 2013 - Am Soc Clin Investig
Whether facultative β cell progenitors exist in the adult pancreas is a major unsolved
question. To date, lineage-tracing studies have provided conflicting results. To track β cell …
question. To date, lineage-tracing studies have provided conflicting results. To track β cell …
The β-cell/EC axis: how do islet cells talk to each other?
Within the pancreatic islet, the β-cell represents the ultimate biosensor. Its central function is
to accurately sense glucose levels in the blood and consequently release appropriate …
to accurately sense glucose levels in the blood and consequently release appropriate …
[HTML][HTML] Intra-islet endothelial cell and β-cell crosstalk: Implication for islet cell transplantation
S Narayanan, G Loganathan… - World journal of …, 2017 - ncbi.nlm.nih.gov
The intra-islet microvasculature is a critical interface between the blood and islet endocrine
cells governing a number of cellular and pathophysiological processes associated with the …
cells governing a number of cellular and pathophysiological processes associated with the …
[HTML][HTML] Placental growth factor promotes metastases of ovarian cancer through MiR-543-regulated MMP7
N Song, H Liu, X Ma, S Zhang - Cellular Physiology and Biochemistry, 2015 - karger.com
Background/Aims: Elucidation of the molecular mechanisms underlying ovarian cancer (OC)
cell invasion and migration may provide important evidence for developing efficient therapy …
cell invasion and migration may provide important evidence for developing efficient therapy …
[HTML][HTML] Improved therapeutic effects on diabetic foot by human mesenchymal stem cells expressing MALAT1 as a sponge for microRNA-205-5p
L Zhu, Q Zhong, T Yang, X Xiao - Aging (Albany NY), 2019 - ncbi.nlm.nih.gov
Diabetic foot (DF) is a common complication of high severity for diabetes, a prevalent
metabolic disorder that affects billions of people worldwide. Mesenchymal stem cells (MSCs) …
metabolic disorder that affects billions of people worldwide. Mesenchymal stem cells (MSCs) …
Pancreatic duct cells as a source of VEGF in mice
X Xiao, K Prasadan, P Guo, Y El-Gohary, S Fischbach… - Diabetologia, 2014 - Springer
Aims/hypothesis Vascular endothelial growth factor (VEGF) is essential for proper pancreatic
development, islet vascularisation and insulin secretion. In the adult pancreas, VEGF is …
development, islet vascularisation and insulin secretion. In the adult pancreas, VEGF is …