Importance There are many known acquired risk factors for cerebral palsy (CP), but in some
cases, CP is evident without risk factors (cryptogenic CP). Early CP cohort studies report a …

Cerebral palsy is a clinical descriptor covering a diverse group of permanent, non-
degenerative disorders of motor function. Around one-third of cases have now been shown …

We performed whole-genome sequencing (WGS) in 327 children with cerebral palsy (CP)
and their biological parents. We classified 37 of 327 (11.3%) children as having …

Importance Exome sequencing is a first-tier diagnostic test for individuals with
neurodevelopmental disorders, including intellectual disability/developmental delay and …

Cerebral palsy (CP) is a debilitating condition characterized by abnormal movement or
posture, beginning early in development. Early family and twin studies and more recent …

Profiles of sleep duration and timing and corresponding electroencephalographic activity
reflect brain changes that support cognitive and behavioral maturation and may provide …

Objective To explore the genetic spectrum of cerebral palsy (CP) in a Chinese pediatric
cohort. Study design This was a retrospective observational study of patients with CP from …

Background IFIH1 variants have been reported to be associated with immune-related
disorders with/without seizures. It is unknown whether IFIH1 variants are associated with …

A growing number of genes have been identified in individuals with cerebral palsy (CP);
however, many of these studies have poor compliance with the cerebral palsy clinical …

Objective Hereditary spastic paraplegia (HSP) is a highly heterogeneous neurologic
disorder characterized by lower‐extremity spasticity. Here, we set out to determine the …