[HTML][HTML] DENV-specific IgA contributes protective and non-pathologic function during antibody-dependent enhancement of DENV infection

AD Wegman, MJ Waldran, LE Bahr, JQ Lu… - PLoS …, 2023 - journals.plos.org
Dengue represents a growing public health burden worldwide, accounting for approximately
100 million symptomatic cases and tens of thousands of fatalities yearly. Prior infection with …

Antibody-Dependent dengue virus entry modulates cell intrinsic responses for enhanced infection

CYY Chan, JZH Low, ES Gan, EZ Ong, SLX Zhang… - Msphere, 2019 - Am Soc Microbiol
Dengue is caused by infection with any one of four dengue viruses (DENV); the risk of
severe disease appears to be enhanced by the cross-reactive or subneutralizing levels of …

The mechanistic role of antibodies to dengue virus in protection and disease pathogenesis

ES Gan, DHR Ting, KR Chan - Expert Review of Anti-Infective …, 2017 - Taylor & Francis
Introduction: Dengue is a prevalent disease in tropical and subtropical countries with an
estimated 400 million people infected annually. While significant advancement has been …

[HTML][HTML] Blockade of dengue virus entry into myeloid cells by endocytic inhibitors in the presence or absence of antibodies

AC Carro, LE Piccini, EB Damonte - PLoS neglected tropical …, 2018 - journals.plos.org
Background Dengue is the most prevalent arthropod-borne viral human disease in tropical
and subtropical regions, caused by four dengue virus (DENV) serotypes. In spite of the …

The antibodies against the A137R protein drive antibody-dependent enhancement of African swine fever virus infection in porcine alveolar macrophages

X Yang, E Sun, H Zhai, T Wang, S Wang… - Emerging Microbes & …, 2024 - Taylor & Francis
African swine fever virus (ASFV) is the causative agent of African swine fever (ASF), a highly
contagious disease that can kill up to 100% of domestic pigs and wild boars. It has been …

[HTML][HTML] Human Schwann cells are susceptible to infection with Zika and yellow fever viruses, but not dengue virus

G Dhiman, R Abraham, DE Griffin - Scientific reports, 2019 - nature.com
Zika virus (ZIKV) is a re-emerged flavivirus transmitted by Aedes spp mosquitoes that has
caused outbreaks of fever and rash on islands in the Pacific and in the Americas. These …

[HTML][HTML] The role of autophagy in asparaginase-induced immune suppression of macrophages

P Song, Z Wang, X Zhang, J Fan, Y Li, Q Chen… - Cell death & …, 2017 - nature.com
Erwinia asparaginase, a bacteria-derived enzyme drug, has been used in the treatment of
various cancers, especially acute lymphoblastic leukemia (ALL). One of the most significant …

[HTML][HTML] Amplificación de la infección dependiente de anticuerpos en la inmunopatogénesis del dengue grave, implicaciones para el desarrollo y uso de las vacunas

BA Cáceres Munar, JE Castellanos Parra… - Acta biológica …, 2019 - scielo.org.co
Actualmente, la infección por el virus de dengue (DENV) es uno de los problemas más
importantes de salud pública en países tropicales y endémicos como Colombia, pues en …

[HTML][HTML] Human plasmacytoid dendritic cells at the crossroad of type I interferon-regulated B cell differentiation and antiviral response to tick-borne encephalitis virus

MP Etna, A Signorazzi, D Ricci, M Severa… - PLoS …, 2021 - journals.plos.org
The Tick-borne encephalitis virus (TBEV) causes different disease symptoms varying from
asymptomatic infection to severe encephalitis and meningitis suggesting a crucial role of the …

Hypoxia enhances antibody‐dependent dengue virus infection

ES Gan, WF Cheong, KR Chan, EZ Ong, X Chai… - The EMBO …, 2017 - embopress.org
Dengue virus (DENV) has been found to replicate in lymphoid organs such as the lymph
nodes, spleen, and liver in post‐mortem analysis. These organs are known to have low …