The roles of tumor-derived exosomes in non-small cell lung cancer and their clinical implications

H Zheng, Y Zhan, S Liu, J Lu, J Luo, J Feng… - Journal of Experimental & …, 2018 - Springer
Non-small cell lung cancer (NSCLC) accounts for approximately 85% of lung cancer cases,
and it is one of the leading causes of cancer death in both men and women worldwide due …

siRNA delivery to the lung: what's new?

OM Merkel, I Rubinstein, T Kissel - Advanced drug delivery reviews, 2014 - Elsevier
RNA interference (RNAi) has been thought of as the general answer to many unmet medical
needs. After the first success stories, it soon became obvious that short interfering RNA …

Exosomes and lung cancer: roles in pathophysiology, diagnosis and therapeutic applications

A Amiri, MH Pourhanifeh, HR Mirzaei… - Current medicinal …, 2021 - ingentaconnect.com
Lung cancer is a malignancy with a high morbidity and mortality rate, and affected patients
have low survival and poor prognosis. The therapeutic approaches for the treatment of this …

Nanomaterials in cancer-therapy drug delivery system

G Zhang, X Zeng, P Li - Journal of biomedical nanotechnology, 2013 - ingentaconnect.com
Nanomaterials can enhance the delivery and treatment efficiency of anti-cancer drugs, and
the mechanisms of the tumorreducing activity of nanomaterials with cancer drug have been …

Research progress of matrine's anticancer activity and its molecular mechanism

F Chen, Y Pan, J Xu, B Liu, H Song - Journal of Ethnopharmacology, 2022 - Elsevier
Background and ethnopharmacological relevance: Matrine (MT), a type of alkaloid extracted
from the Sophora family of traditional Chinese medicine, has been documented to exert a …

Advances in combination therapy of lung cancer: Rationales, delivery technologies and dosage regimens

L Wu, D Leng, D Cun, C Foged, M Yang - Journal of Controlled Release, 2017 - Elsevier
Lung cancer is a complex disease caused by a multitude of genetic and environmental
factors. The progression of lung cancer involves dynamic changes in the genome and a …

MicroRNA-203 is a prognostic indicator in bladder cancer and enhances chemosensitivity to cisplatin via apoptosis by targeting Bcl-w and survivin

X Zhang, Y Zhang, X Liu, A Fang, P Li, Z Li, T Liu… - PloS one, 2015 - journals.plos.org
Resistance to cisplatin-based chemotherapy is a major cause of treatment failure in
advanced bladder cancer (BC) patients. There is increasing evidence that microRNAs are …

[HTML][HTML] Development of small RNA delivery systems for lung cancer therapy

Y Fujita, K Kuwano, T Ochiya - International journal of molecular sciences, 2015 - mdpi.com
RNA interference (RNAi) has emerged as a powerful tool for studying target identification
and holds promise for the development of therapeutic gene silencing. Recent advances in …

Overcoming multiple drug resistance in lung cancer using siRNA targeted therapy

S Naghizadeh, A Mohammadi, B Baradaran… - Gene, 2019 - Elsevier
Among cancers, lung cancer is the most morbidity and mortality disease that is remaining
the fatalist. Generally, there are multiple treatment procedures for lung cancer, such as …

miR‑140‑3p enhances cisplatin sensitivity and attenuates stem cell‑like properties through repressing Wnt/β‑catenin signaling in lung adenocarcinoma cells

S Wu, H Wang, Y Pan, X Yang… - Experimental and …, 2020 - spandidos-publications.com
Lung adenocarcinoma (LUAD) is the most predominant subtype of non‑small cell lung
cancer (NSCLC) that is experiencing the fastest growth rate in incidence. Chemoresistance …