Retinal determination gene networks: from biological functions to therapeutic strategies
S Zhu, W Li, H Zhang, Y Yan, Q Mei, K Wu - Biomarker Research, 2023 - Springer
The retinal determinant gene network (RDGN), originally discovered as a critical
determinator in Drosophila eye specification, has become an important regulatory network in …
determinator in Drosophila eye specification, has become an important regulatory network in …
[HTML][HTML] Engineered hematopoietic and immune cells derived from human pluripotent stem cells
For the past decade, significant advances have been achieved in human hematopoietic
stem cell (HSC) transplantation for treating various blood diseases and cancers. However …
stem cell (HSC) transplantation for treating various blood diseases and cancers. However …
Antileukemic efficacy of a potent artemisinin combined with sorafenib and venetoclax
BS Moses, S McCullough, JM Fox, BT Mott… - Blood …, 2021 - ashpublications.org
Artemisinins are active against human leukemia cell lines and have low clinical toxicity in
worldwide use as antimalarials. Because multiagent combination regimens are necessary to …
worldwide use as antimalarials. Because multiagent combination regimens are necessary to …
Blocking the interaction between circTNRC18 and LIN28A promotes trophoblast epithelial–mesenchymal transformation and alleviates preeclampsia
LL Chen, YQ Li, ZH Kang, X Zhang, SY Gu… - Molecular and Cellular …, 2024 - Elsevier
Defects in migration and invasion caused by dysregulation of trophoblastic epithelial–
mesenchymal transformation (EMT) play a vital role in preeclampsia (PE). We have …
mesenchymal transformation (EMT) play a vital role in preeclampsia (PE). We have …
SIRT3, a metabolic target linked to ataxia-telangiectasia mutated (ATM) gene deficiency in diffuse large B-cell lymphoma
K Bhalla, S Jaber, K Reagan, A Hamburg… - Scientific Reports, 2020 - nature.com
Inactivation of Ataxia-telangiectasia mutated (ATM) gene results in an increased risk to
develop cancer. We show that ATM deficiency in diffuse large B-cell lymphoma (DLBCL) …
develop cancer. We show that ATM deficiency in diffuse large B-cell lymphoma (DLBCL) …
RDGN-based predictive model for the prognosis of breast cancer
B Dong, M Yi, S Luo, A Li, K Wu - Experimental hematology & oncology, 2020 - Springer
Background Breast cancer is the most diagnosed malignancy in females in the United
States. The members of retinal determination gene network (RDGN) including DACH, EYA …
States. The members of retinal determination gene network (RDGN) including DACH, EYA …
Aberrant GPA expression and regulatory function of red blood cells in sickle cell disease
JN Marshall, MN Klein, P Karki, K Promnares… - Blood …, 2024 - ashpublications.org
Glycophorin A (GPA), a red blood cell (RBC) surface glycoprotein, can maintain peripheral
blood leukocyte quiescence through interaction with a sialic acid–binding Ig-like lectin …
blood leukocyte quiescence through interaction with a sialic acid–binding Ig-like lectin …
NKL homeobox genes NKX2-3 and NKX2-4 deregulate megakaryocytic-erythroid cell differentiation in AML
S Nagel, C Pommerenke, C Meyer… - International Journal of …, 2021 - mdpi.com
NKL homeobox genes encode transcription factors that impact normal development and
hematopoietic malignancies if deregulated. Recently, we established an NKL-code that …
hematopoietic malignancies if deregulated. Recently, we established an NKL-code that …
[HTML][HTML] 鳃耳综合征/鳃耳肾综合征的遗传学研究进展
陈岸海， 凌捷， 冯永 - Journal of Central South University Medical …, 2022 - ncbi.nlm.nih.gov
鳃耳综合征(branchio-oto syndrome， BOS)/鳃耳肾综合征(branchio-oto-renal syndrome，
BORS) 是一种不常见的常染色体显性遗传综合征型疾病， 人群发病率约为1/40 000 …
BORS) 是一种不常见的常染色体显性遗传综合征型疾病， 人群发病率约为1/40 000 …
Genetic research progress in branchio-oto syndrome/branchio-oto-renal syndrome.
A Chen, J Ling, Y Feng - Zhong nan da xue xue bao. Yi xue ban …, 2022 - europepmc.org
鳃耳综合征 (branchio-oto syndrome, BOS)/鳃耳肾综合征 (branchio-oto-renal syndrome,
BORS) 是一种不常见的常染色体显性遗传综合征型疾病, 人群发病率约为 1/40 000 …
BORS) 是一种不常见的常染色体显性遗传综合征型疾病, 人群发病率约为 1/40 000 …