Small molecule metabolites: discovery of biomarkers and therapeutic targets
S Qiu, Y Cai, H Yao, C Lin, Y Xie, S Tang… - Signal Transduction and …, 2023 - nature.com
Metabolic abnormalities lead to the dysfunction of metabolic pathways and metabolite
accumulation or deficiency which is well-recognized hallmarks of diseases. Metabolite …
accumulation or deficiency which is well-recognized hallmarks of diseases. Metabolite …
Leptin in Leanness and Obesity: JACC State-of-the-Art Review
N Perakakis, OM Farr, CS Mantzoros - Journal of the American College of …, 2021 - jacc.org
Leptin has emerged over the past 2 decades as a key hormone secreted by adipose tissue
that conveys information on energy stores. Leptin is considered an important regulator of …
that conveys information on energy stores. Leptin is considered an important regulator of …
From non-alcoholic fatty liver disease (NAFLD) to steatotic liver disease (SLD): an ongoing journey towards refining the terminology for this prevalent metabolic …
M Kokkorakis, C Boutari, N Katsiki… - Metabolism-Clinical …, 2023 - metabolismjournal.com
Non-alcoholic fatty liver disease (NAFLD) is a prevalent metabolic condition closely
associated with genetic predisposition and/or obesity, lipodystrophy, and insulin resistance …
associated with genetic predisposition and/or obesity, lipodystrophy, and insulin resistance …
Liver biopsy-based validation, confirmation and comparison of the diagnostic performance of established and novel non-invasive steatotic liver disease indexes …
M Kouvari, L Valenzuela-Vallejo, V Guatibonza-Garcia… - Metabolism, 2023 - Elsevier
Background Non-invasive tools (NIT) for metabolic-dysfunction associated liver disease
(MASLD) screening or diagnosis need to be thoroughly validated using liver biopsies …
(MASLD) screening or diagnosis need to be thoroughly validated using liver biopsies …
[HTML][HTML] Nutraceutical approaches to non-alcoholic fatty liver disease (NAFLD): A position paper from the International Lipid Expert Panel (ILEP)
Abstract Non-Alcoholic Fatty Liver Disease (NAFLD) is a common condition affecting around
10–25% of the general adult population, 15% of children, and even> 50% of individuals who …
10–25% of the general adult population, 15% of children, and even> 50% of individuals who …
Diagnostic modalities of non-alcoholic fatty liver disease: from biochemical biomarkers to multi-omics non-invasive approaches
E Martinou, M Pericleous, I Stefanova, V Kaur… - Diagnostics, 2022 - mdpi.com
Non-Alcoholic Fatty Liver Disease (NAFLD) is currently the most common cause of chronic
liver disease worldwide, and its prevalence is increasing globally. NAFLD is a multifaceted …
liver disease worldwide, and its prevalence is increasing globally. NAFLD is a multifaceted …
Perspectives on precision medicine approaches to NAFLD diagnosis and management
Precision medicine defines the attempt to identify the most effective approaches for specific
subsets of patients based on their genetic background, clinical features, and environmental …
subsets of patients based on their genetic background, clinical features, and environmental …
Time to transition from a negative nomenclature describing what NAFLD is not, to a novel, pathophysiology-based, umbrella classification of fatty liver disease (FLD)
L Valenzuela-Vallejo, CS Mantzoros - Metabolism, 2022 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is a definition of a prevalent condition that has
been given a name describing what the disease is not, mainly due to gaps in the …
been given a name describing what the disease is not, mainly due to gaps in the …
Precision medicine in fatty liver disease/non-alcoholic fatty liver disease
L Valenzuela-Vallejo, D Sanoudou… - Journal of Personalized …, 2023 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is the most prevalent chronic liver disease, and is
related to fatal and non-fatal liver, metabolic, and cardiovascular complications. Its non …
related to fatal and non-fatal liver, metabolic, and cardiovascular complications. Its non …
Liver fat as risk factor of hepatic and cardiometabolic diseases
M Demir, SR Bornstein, CS Mantzoros… - Obesity …, 2023 - Wiley Online Library
Non‐alcoholic fatty liver disease (NAFLD) is a disorder characterized by excessive
accumulation of fat in the liver that can progress to liver inflammation (non‐alcoholic …
accumulation of fat in the liver that can progress to liver inflammation (non‐alcoholic …