Roles of adipokines in digestive diseases: markers of inflammation, metabolic alteration and disease progression

ML Chang, Z Yang, SS Yang - International journal of molecular sciences, 2020 - mdpi.com
Adipose tissue is a highly dynamic endocrine tissue and constitutes a central node in the
interorgan crosstalk network through adipokines, which cause pleiotropic effects, including …

Role of leptin and adiponectin in carcinogenesis

A Bocian-Jastrzębska, A Malczewska-Herman… - Cancers, 2023 - mdpi.com
Simple Summary The involvement of leptin and adiponectin with receptors in the formation
of many types of cancer as well as their impact on the clinical course of cancer patients are …

Kyoto international consensus report on anatomy, pathophysiology and clinical significance of the gastro-oesophageal junction

K Sugano, SJ Spechler, EM El-Omar, KEL McColl… - Gut, 2022 - gut.bmj.com
Objective An international meeting was organised to develop consensus on (1) the
landmarks to define the gastro-oesophageal junction (GOJ),(2) the occurrence and …

Leptin, both bad and good actor in cancer

C Jiménez-Cortegana, A López-Saavedra… - Biomolecules, 2021 - mdpi.com
Leptin is an important regulator of basal metabolism and food intake, with a pivotal role in
obesity. Leptin exerts many different actions on various tissues and systems, including …

Association of serum levels of adipokines and insulin with risk of Barrett's esophagus: a systematic review and meta-analysis

AK Chandar, S Devanna, C Lu, S Singh, K Greer… - Clinical …, 2015 - Elsevier
Background & Aims Metabolically active visceral fat may be associated with esophageal
inflammation, metaplasia, and neoplasia. We performed a meta-analysis to evaluate the …

The troublesome epidemiology of Barrett's esophagus and esophageal adenocarcinoma

JL Schneider, DA Corley - Gastrointestinal Endoscopy Clinics, 2017 - giendo.theclinics.com
Esophageal adenocarcinoma is a highly fatal neoplasm of the esophagus, which has
surpassed esophageal squamous cell carcinoma as the most common form of esophageal …

Exploiting significance of physical exercise in prevention of gastrointestinal disorders

J Bilski, A Mazur-Bialy, M Magierowski… - Current …, 2018 - ingentaconnect.com
Background: Physical activity can be involved in the prevention of gastrointestinal (GI)-tract
diseases, however, the results regarding the volume and the intensity of exercise …

Circulating levels of inflammatory and metabolic biomarkers and risk of esophageal adenocarcinoma and Barrett esophagus: systematic review and meta-analysis

SH Xie, S Rabbani, E Ness-Jensen… - … , Biomarkers & Prevention, 2020 - AACR
Associations between circulating levels of obesity-related biomarkers and risk of
esophageal adenocarcinoma and Barrett esophagus have been reported, but the results are …

Role of obesity, physical exercise, adipose tissue-skeletal muscle crosstalk and molecular advances in Barrett's esophagus and esophageal adenocarcinoma

J Bilski, M Pinkas, D Wojcik-Grzybek… - International Journal of …, 2022 - mdpi.com
Both obesity and esophageal adenocarcinoma (EAC) rates have increased sharply in the
United States and Western Europe in recent years. EAC is a classic example of obesity …

Impact of obesity‑associated myeloid‑derived suppressor cells on cancer risk and progression

C Jiménez‑Cortegana… - International …, 2024 - spandidos-publications.com
Obesity is a chronic disease caused by the accumulation of excessive adipose tissue. This
disorder is characterized by chronic low‑grade inflammation, which promotes the release of …