Redox signaling and metabolism in Alzheimer's disease
MI Holubiec, M Gellert… - Frontiers in Aging …, 2022 - frontiersin.org
Reduction and oxidation reactions are essential for biochemical processes. They are part of
metabolic pathways and signal transduction. Reactive oxygen species (ROS) as second …
metabolic pathways and signal transduction. Reactive oxygen species (ROS) as second …
[HTML][HTML] The plasma membrane Ca2+-ATPase, a molecular target for Tau-induced cytosolic calcium dysregulation
M Berrocal, AM Mata - Neuroscience, 2023 - Elsevier
Abstract Disruption of calcium (Ca 2+) homeostasis is emerging as a prevalent feature of
aging and aging-associated neurodegenerative diseases, including Alzheimer's disease …
aging and aging-associated neurodegenerative diseases, including Alzheimer's disease …
Physiological expression of mutated TAU impaired astrocyte activity and exacerbates β-amyloid pathology in 5xFAD mice
D Farfara, M Sooliman, L Avrahami, TG Royal… - Journal of …, 2023 - Springer
Background Alzheimer's disease (AD) is the leading cause of dementia in the world. The
pathology of AD is affiliated with the elevation of both tau (τ) and β-amyloid (Aβ) pathologies …
pathology of AD is affiliated with the elevation of both tau (τ) and β-amyloid (Aβ) pathologies …
[HTML][HTML] Protective effects of Tenebrio molitor and Protaetia brevitarsis seulensis extracts on aging: Regulation of blood–brain barrier, amyloid β plaques, and intestinal …
NB Tran, H Lee, SJ Lee - Journal of Functional Foods, 2024 - Elsevier
Insects are considered as a potentially eco-friendly, highly nutritious, and protein-rich food
source. We evaluated the effects of Tenebrio molitor (Tm) and Protaetia brevitarsis seulensis …
source. We evaluated the effects of Tenebrio molitor (Tm) and Protaetia brevitarsis seulensis …
Amyloid Precursor Protein and Tau Peptides Linked Together Ameliorate Loss of Cognition in an Alzheimer's Disease Animal Model
The major proteins involved in Alzheimer's disease (AD) are amyloid precursor protein
(APP) and Tau. We demonstrate that APP1 (390–412) and Tau1 (19–34), linked together …
(APP) and Tau. We demonstrate that APP1 (390–412) and Tau1 (19–34), linked together …
The transmembrane amyloid precursor C99 protein exhibits non-specific interaction with tau
Historically, the two most prominent proteins in Alzheimer's disease (AD) research have
been the amyloid precursor protein (APP) and the microtubule assembly protein tau. In the …
been the amyloid precursor protein (APP) and the microtubule assembly protein tau. In the …
Store-operated Ca2+ entry regulatory factor (SARAF) alters murine metabolic state in an age-dependent manner via hypothalamic pathways
Summary Store-operated Ca2+ entry (SOCE) is a vital process aimed at refilling cellular
internal Ca2+ stores, and a primary cellular signaling driver of transcription factors entry to …
internal Ca2+ stores, and a primary cellular signaling driver of transcription factors entry to …
The Plasma Membrane Ca2+-ATPase, a Molecular Target for Tau-induced Cytosolic Calcium Dysregulation
M Berrocal Carrillo, AM Mata Durán - 2022 - dehesa.unex.es
Disruption of calcium (Ca2+) homeostasis is emerging as a prevalent feature of aging and
agingassociated neurodegenerative diseases, including Alzheimer's disease (AD), the most …
agingassociated neurodegenerative diseases, including Alzheimer's disease (AD), the most …
Advanced techniques for the study of membrane proteins in complex and native lipid environments.
JM Hutchison - 2021 - ir.vanderbilt.edu
The biophysical and biochemical study of membrane proteins is uniquely challenged by the
lipid bilayer environment in which membrane proteins reside. While fantastic methods have …
lipid bilayer environment in which membrane proteins reside. While fantastic methods have …