Abdominal obesity, adipokines and non-communicable diseases

D Dhawan, S Sharma - The Journal of steroid biochemistry and molecular …, 2020 - Elsevier
Abdominal obesity may be defined as excess deposits of fat in the abdominal region. It is a
common health condition seen in South Asians and is positively related to non …

Oxidative stress and metabolic disorders: Pathogenesis and therapeutic strategies

V Rani, G Deep, RK Singh, K Palle, UCS Yadav - Life sciences, 2016 - Elsevier
Increased body weight and metabolic disorder including insulin resistance, type 2 diabetes
and cardiovascular complications together constitute metabolic syndrome. The …

RhoA/Rho-kinase in the cardiovascular system

H Shimokawa, S Sunamura, K Satoh - Circulation research, 2016 - Am Heart Assoc
Twenty years ago, Rho-kinase was identified as an important downstream effector of the
small GTP-binding protein, RhoA. Thereafter, a series of studies demonstrated the important …

Dietary pattern analysis and biomarkers of low-grade inflammation: a systematic literature review

J Barbaresko, M Koch, MB Schulze… - Nutrition …, 2013 - academic.oup.com
The purpose of the present literature review was to investigate and summarize the current
evidence on associations between dietary patterns and biomarkers of inflammation, as …

Adiponectin regulation and function

H Fang, RL Judd - Comprehensive Physiology, 2011 - Wiley Online Library
Adipose tissue is now recognized as an important endocrine organ, capable of secreting a
large number of endocrine factors which regulate a wide variety of physiological functions …

Inflammation in atherosclerosis: transition from theory to practice

P Libby, Y Okamoto, VZ Rocha, E Folco - Circulation journal, 2010 - jstage.jst.go.jp
LIBBY P et al. the procoagulant tissue factor (TF). 2–5 Examples of specific mediators
involved in initiation of atherosclerotic plaques include vascular cell adhesion molecule-1 …

[HTML][HTML] Type 2 diabetes mellitus and cardiovascular disease: genetic and epigenetic links

S De Rosa, B Arcidiacono, E Chiefari… - Frontiers in …, 2018 - frontiersin.org
Type 2 diabetes mellitus (DM) is a common metabolic disorder predisposing to diabetic
cardiomyopathy and atherosclerotic cardiovascular disease (CVD), which could lead to …

SIRT3–AMP-activated protein kinase activation by nitrite and metformin improves hyperglycemia and normalizes pulmonary hypertension associated with heart failure …

YC Lai, DM Tabima, JJ Dube, KS Hughan… - Circulation, 2016 - Am Heart Assoc
Background—Pulmonary hypertension associated with heart failure with preserved ejection
fraction (PH-HFpEF) is an increasingly recognized clinical complication of metabolic …

[HTML][HTML] T-cadherin is critical for adiponectin-mediated cardioprotection in mice

MS Denzel, MC Scimia, PM Zumstein… - The Journal of …, 2010 - Am Soc Clin Investig
The circulating, adipocyte-secreted hormone adiponectin (APN) exerts protective effects on
the heart under stress conditions. The receptors binding APN to cardiac tissue, however …

ADIPOQ/adiponectin induces cytotoxic autophagy in breast cancer cells through STK11/LKB1-mediated activation of the AMPK-ULK1 axis

SJ Chung, GP Nagaraju, A Nagalingam, N Muniraj… - Autophagy, 2017 - Taylor & Francis
ABSTRACT ADIPOQ/adiponectin, an adipocytokine secreted by adipocytes in the breast
tumor microenvironment, negatively regulates cancer cell growth hence increased levels of …