S100B is a calcium-binding protein mainly concentrated in astrocytes in the nervous system.
Its levels in biological fluids are recognized as a reliable biomarker of active neural distress …

Purpose Glial activation is one of the earliest mechanisms to be altered in Alzheimer's
disease (AD). Glial fibrillary acidic protein (GFAP) relates to reactive astrogliosis and can be …

In the past years, neuroinflammation has been widely investigated in Alzheimer's disease
(AD). Evidence from animal, in vivo and post-mortem studies has shown that inflammatory …

INTRODUCTION Our objective was determining the optimal combinations of cerebrospinal
fluid (CSF) biomarkers for predicting disease progression in Alzheimer's disease (AD) and …

Neuroinflammation is a hallmark of Alzheimer's disease (AD) and both positive and negative
associations of individual inflammation-related markers with brain structure and cognitive …

Introduction This study examined plasma glial fibrillary acidic protein (GFAP) as a biomarker
of cognitive impairment due to Alzheimer's disease (AD) with and against plasma …

Some evidence suggests a biphasic pattern of changes in cortical thickness wherein higher,
rather than lower, thickness is associated with very early Alzheimer's disease (AD) …

Objective Patients with Alzheimer's disease (AD) have diffuse brain atrophy, but some
regions, such as the anterior cingulate cortex (ACC), are spared and may even show …

Background Despite the high sensitivity of cerebrospinal fluid (CSF) amyloid beta (Aβ) 42 to
detect amyloid pathology, the Aβ42/Aβ40 ratio (amyR) better estimates amyloid load, with …

Glial and microglial cells contribute to brain glucose consumption and could actively
participate in shaping patterns of brain hypometabolism. Here, we aimed to investigate the …