Recent advances in encapsulation, protection, and oral delivery of bioactive proteins and peptides using colloidal systems

SL Perry, DJ McClements - Molecules, 2020 - mdpi.com
There are many areas in medicine and industry where it would be advantageous to orally
deliver bioactive proteins and peptides (BPPs), including ACE inhibitors, antimicrobials …

Monoglyceride self-assembly structures as delivery vehicles

L Sagalowicz, ME Leser, HJ Watzke… - Trends in Food Science & …, 2006 - Elsevier
Monoglyceride molecules spontaneously self-assemble into various liquid crystalline
structures when present in an aqueous environment. The various phases can be used to …

Self-Assembled Structures and pKa Value of Oleic Acid in Systems of Biological Relevance

S Salentinig, L Sagalowicz, O Glatter - Langmuir, 2010 - ACS Publications
In the human digestion process, triglycerides are hydrolyzed by lipases to monoglycerides
and the corresponding fatty acids. Here we report the self-assembly of structures in …

Lipid crystallization: from self-assembly to hierarchical and biological ordering

CV Kulkarni - Nanoscale, 2012 - pubs.rsc.org
Lipid crystallization is ubiquitous in nature, observed in biological structures as well as in
commercial products and applications. In a dehydrated state most of the lipids form well …

Electron microscopy of pharmaceutical systems

V Klang, C Valenta, NB Matsko - Micron, 2013 - Elsevier
During the last decades, the focus of research in pharmaceutical technology has steadily
shifted towards the development and optimisation of nano-scale drug delivery systems. As a …

Light-responsive molecular release from cubosomes using swell-squeeze lattice control

BE Jones, EA Kelly, N Cowieson… - Journal of the …, 2022 - ACS Publications
Stimuli-responsive materials are crucial to advance controlled delivery systems for drugs
and catalysts. Lyotropic liquid crystals (LLCs) have well-defined internal structures suitable …

PEGylation of Phosphatidylglycerol/Docosahexaenoic Acid Hexosomes with d-α-Tocopheryl Succinate Poly(ethylene glycol)2000 Induces Morphological …

G Bor, JH Lin, KY Lin, HC Chen… - … Applied Materials & …, 2022 - ACS Publications
Considering the broad therapeutic potential of omega-3 polyunsaturated fatty acids such as
docosahexaenoic acid (DHA), here we study the effect of PEGylation of DHA-incorporated …

From structure to function: pH-switchable antimicrobial nano-self-assemblies

M Gontsarik, A Yaghmur, Q Ren… - … applied materials & …, 2018 - ACS Publications
Stimuli-responsive nanocarriers based on lipid self-assemblies have the potential to provide
targeted delivery of antimicrobial peptides, limiting their side effects while protecting them …

Engineering nanomedicines for improved melanoma therapy: progress and promises

D Bei, J Meng, BBC Youan - Nanomedicine, 2010 - Taylor & Francis
Once metastatic, melanoma remains one of the most aggressive and morbid malignancies.
Moreover, in past decades, the overall survival for advanced unresectable melanoma …

Oil-Loaded Monolinolein-Based Particles with Confined Inverse Discontinuous Cubic Structure (Fd3m)

A Yaghmur, L De Campo, S Salentinig, L Sagalowicz… - Langmuir, 2006 - ACS Publications
In our recent work, we reported on the effect of varying temperature and solubilizing
tetradecane (TC) on the structural transitions observed in dispersed particles based on the …