Malaria during pregnancy
M Fried, PE Duffy - Cold Spring Harbor …, 2017 - perspectivesinmedicine.cshlp.org
One hundred and twenty-five million women in malaria-endemic areas become pregnant
each year (see Dellicour et al. PLoS Med 7: e1000221 [2010]) and require protection from …
each year (see Dellicour et al. PLoS Med 7: e1000221 [2010]) and require protection from …
Malaria in pregnancy: pathogenesis and immunity
Understanding of the biological basis for susceptibility to malaria in pregnancy was recently
advanced by the discovery that erythrocytes infected with Plasmodium falciparum …
advanced by the discovery that erythrocytes infected with Plasmodium falciparum …
Selective upregulation of a single distinctly structured var gene in chondroitin sulphate A‐adhering Plasmodium falciparum involved in pregnancy‐associated …
Cytoadhesion of infected red blood cells (iRBC) is mediated through parasite‐encoded,
clonally variant surface antigens (VSA) and is a central process in the pathogenesis of …
clonally variant surface antigens (VSA) and is a central process in the pathogenesis of …
Evidence for the involvement of VAR2CSA in pregnancy-associated malaria
In Plasmodium falciparum–endemic areas, pregnancy-associated malaria (PAM) is an
important health problem. The condition is precipitated by accumulation of parasite-infected …
important health problem. The condition is precipitated by accumulation of parasite-infected …
Immune effector mechanisms in malaria
K Marsh, S Kinyanjui - Parasite immunology, 2006 - Wiley Online Library
That humans in endemic areas become immune to malaria offers encouragement to the
idea of developing protective vaccines. However natural immunity is relatively inefficient …
idea of developing protective vaccines. However natural immunity is relatively inefficient …
[HTML][HTML] Malaria in pregnancy: from placental infection to its abnormal development and damage
CLL Chua, SKM Khoo, JLE Ong… - Frontiers in …, 2021 - frontiersin.org
Malaria remains a global health burden with Plasmodium falciparum accounting for the
highest mortality and morbidity. Malaria in pregnancy can lead to the development of …
highest mortality and morbidity. Malaria in pregnancy can lead to the development of …
HIV and co‐infections
CC Chang, M Crane, JL Zhou, M Mina… - Immunological …, 2013 - Wiley Online Library
Despite significant reductions in morbidity and mortality secondary to availability of effective
combination anti‐retroviral therapy (cART), human immunodeficiency virus (HIV) infection …
combination anti‐retroviral therapy (cART), human immunodeficiency virus (HIV) infection …
[HTML][HTML] Afucosylated Plasmodium falciparum-specific IgG is induced by infection but not by subunit vaccination
MD Larsen, M Lopez-Perez, EK Dickson… - Nature …, 2021 - nature.com
Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) family members mediate
receptor-and tissue-specific sequestration of infected erythrocytes (IEs) in malaria. Antibody …
receptor-and tissue-specific sequestration of infected erythrocytes (IEs) in malaria. Antibody …
Variant surface antigen-specific IgG and protection against clinical consequences of pregnancy-associated Plasmodium falciparum malaria
T Staalsoe, CE Shulman, JN Bulmer, K Kawuondo… - The Lancet, 2004 - thelancet.com
Background Pregnancy-associated malaria caused by Plasmodium falciparum adherence to
chondroitin sulfate A in the placental intervillous space is a major cause of low birthweight …
chondroitin sulfate A in the placental intervillous space is a major cause of low birthweight …
Widespread functional specialization of Plasmodium falciparum erythrocyte membrane protein 1 family members to bind CD36 analysed across a parasite genome
BA Robinson, TL Welch, JD Smith - Molecular microbiology, 2003 - Wiley Online Library
Plasmodium falciparum‐infected erythrocytes sequester from blood circulation by binding
host endothelium. A large family of variant proteins mediates cytoadherence and their …
host endothelium. A large family of variant proteins mediates cytoadherence and their …