COVID‐19: Clinical status of vaccine development to date
S Kumar, M Basu, P Ghosh, A Ansari… - British Journal of …, 2023 - Wiley Online Library
Severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2)‐induced COVID‐19 is a
complicated disease. Clinicians are continuously facing difficulties to treat infected patients …
complicated disease. Clinicians are continuously facing difficulties to treat infected patients …
COVID-19 therapeutics: Clinical application of repurposed drugs and futuristic strategies for target-based drug discovery
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) causes the complicated
disease COVID-19. Clinicians are continuously facing huge problems in the treatment of …
disease COVID-19. Clinicians are continuously facing huge problems in the treatment of …
An exosome-based specific transcriptomic signature for profiling regulation patterns and modifying tumor immune microenvironment infiltration in triple-negative …
H Wang, R Wang, L Luo, J Hong, X Chen… - Frontiers in …, 2023 - frontiersin.org
Triple-negative breast cancer (TNBC) is a highly heterogeneous tumor that lacks effective
treatment and has a poor prognosis. Exosomes carry abundant genomic information and …
treatment and has a poor prognosis. Exosomes carry abundant genomic information and …
PD-1/PD-L1 axis induced host immunosuppression via PI3K/Akt/mTOR signalling pathway in piglets infected by Glaesserella Parasuis
J Li, S Liu, Q Dong, Y Fu, Y Sun, R Luo, X Tian… - BMC Veterinary …, 2024 - Springer
Glaesserella parasuis, an important respiratory bacterial pathogen, causes Glässer's
disease in piglets, with potential immunosuppression. We established a piglet infection …
disease in piglets, with potential immunosuppression. We established a piglet infection …
[HTML][HTML] NSUN2/YBX1 promotes the progression of breast cancer by enhancing HGH1 mRNA stability through m5C methylation
X Zhang, K An, X Ge, Y Sun… - Breast Cancer …, 2024 - breast-cancer-research …
RNA m5C methylation has been extensively implicated in the occurrence and development
of tumors. As the main methyltransferase, NSUN2 plays a crucial regulatory role across …
of tumors. As the main methyltransferase, NSUN2 plays a crucial regulatory role across …
Immunotherapy: Review of the Existing Evidence and Challenges in Breast Cancer
Y Hu, Y Li, Z Yao, F Huang, H Cai, H Liu, X Zhang… - Cancers, 2023 - mdpi.com
Simple Summary Breast cancer is one of the most common malignant tumors in women. Its
incidence rate accounts for 7–10% of all kinds of malignant tumors in the whole body …
incidence rate accounts for 7–10% of all kinds of malignant tumors in the whole body …
Next-generation biomarkers for prognostic and potential therapeutic enhancement in Triple negative breast cancer
R Banerjee, I Maitra, T Bhattacharya… - Critical Reviews in …, 2024 - Elsevier
Triple-negative breast carcinoma (TNBC) is one of the most challenging subtypes of breast
carcinoma and it has very limited therapeutic options as it is highly aggressive. The …
carcinoma and it has very limited therapeutic options as it is highly aggressive. The …
COVID-19 and cancer: insights into their association and influence on genetic and epigenetic landscape
The COVID-19 outbreak has created disaster globally, and mankind is yet to come in terms
with combating this global menace. Amid this turmoil, immunocompromised individuals like …
with combating this global menace. Amid this turmoil, immunocompromised individuals like …
A codelivery system loaded with PDL1-siRNA and sorafenib enhances the therapeutic effect of sorafenib on hepatocellular carcinoma via TAT-poly-SS-lysine modified …
Y Chen, Z Jiang, Z Yan, J Liu, Y Lai, L Li, X Lin… - International Journal of …, 2024 - Elsevier
Sorafenib (SF) is a first-line drug for the treatment of hepatocellular carcinoma (HCC) in
clinical practice. However, acquired drug resistance tremendously limits the clinical efficacy …
clinical practice. However, acquired drug resistance tremendously limits the clinical efficacy …
The immune checkpoint TIGIT/CD155 promotes the exhaustion of CD8+ T cells in TNBC through glucose metabolic reprogramming mediated by PI3K/AKT/mTOR …
M Huang, X Yu, Q Wang, Z Jiang, X Li, W Chen… - Cell Communication and …, 2024 - Springer
Abstract Objective The CD155/TIGIT axis has attracted considerable interest as an emerging
immune checkpoint with potential applications in cancer immunotherapy. Our research …
immune checkpoint with potential applications in cancer immunotherapy. Our research …