Amino acids and their roles in tumor immunotherapy of breast cancer

H Xia, J Zhu, Z Zheng, P Xiao, X Yu… - The Journal of Gene …, 2024 - Wiley Online Library
Breast cancer is the most commonly diagnosed cancer among women. The primary
treatment options include surgery, radiotherapy, chemotherapy, targeted therapy and …

[HTML][HTML] Enhancing immunotherapy efficacy against MHC-I deficient triple-negative breast cancer using LCL161-loaded macrophage membrane-decorated …

W Zhang, Y Zhai, Y Cai, X Gong, Y Jiang… - … Pharmaceutica Sinica B, 2024 - Elsevier
Current cytotoxic T lymphocyte (CTL) activating immunotherapy requires a major
histocompatibility complex I (MHC-I)-mediated presentation of tumor-associated antigens …

Machine learning reveals PANoptosis as a potential reporter and prognostic revealer of tumour microenvironment in lung adenocarcinoma

C Han, Q Danzeng, L Li, S Bai… - The Journal of Gene …, 2024 - Wiley Online Library
Lung adenocarcinoma (LUAD), a prominent lung cancer subtype, has an underexplored
relationship with PANoptosis, a recently discovered mode of tumour cell death. This study …

[HTML][HTML] Distinct genomic and immunologic tumor evolution in germline TP53-driven breast cancers

N Boruah, D Hoyos, R Moses, R Hausler, H Desai… - bioRxiv, 2024 - ncbi.nlm.nih.gov
Pathogenic germline TP53 alterations cause Li-Fraumeni Syndrome (LFS), and breast
cancer is the most common cancer in LFS females. We performed first of its kind multimodal …

[HTML][HTML] New advances in the treatment of chondrosarcoma under the PD-1/PD-L1 pathway

J Yin, P Ren - Journal of Cancer Research and Therapeutics, 2024 - journals.lww.com
Bone sarcomas encompass a group of spontaneous mesenchymal malignancies, among
which osteosarcoma, Ewing sarcoma, chondrosarcoma, and chordoma are the most …

PLGA-based dual-loaded nanoformulation of DIM and TMZ-An advanced clinical strategy for brain cancer treatment in a combinatorial approach

S Sarkar, S Kumar, G Saha, M Basu, MK Ghosh - bioRxiv, 2023 - biorxiv.org
Glioblastoma multiforme (GBM) is a highly aggressive form of primary brain tumor in adults,
which unfortunately has an abysmal prognosis and poor survival rates. Even though several …

ASSOCIAÇÃO DO POLIMORFISMO DO GENE LIGANTE DE MORTE PROGRAMADA-1 (PD-L1) COM O CÂNCER DE MAMA

D de Aragão Bezerra… - REVISTA …, 2024 - ojs.focopublicacoes.com.br
A associação do polimorfismo do gene ligante de morte programada-1 (PD-L1) em
pacientes com câncer de mama não é completamente compreendido. Neste estudo …