Vascular inflammation in hypertension and diabetes: molecular mechanisms and therapeutic interventions
C Savoia, EL Schiffrin - Clinical science, 2007 - portlandpress.com
More than 80% of patients with type 2 diabetes mellitus develop hypertension, and approx.
20% of patients with hypertension develop diabetes. This combination of cardiovascular risk …
20% of patients with hypertension develop diabetes. This combination of cardiovascular risk …
Antiinflammatory effects of angiotensin II subtype 1 receptor blockade in hypertensive patients with microinflammation
D Fliser, K Buchholz, H Haller - Circulation, 2004 - Am Heart Assoc
Background—Experimental studies revealed proinflammatory properties of angiotensin II.
We evaluated antiinflammatory effects of the angiotensin II subtype 1 receptor antagonist …
We evaluated antiinflammatory effects of the angiotensin II subtype 1 receptor antagonist …
Homocysteine induces the expression of C-reactive protein via NMDAr-ROS-MAPK-NF-κB signal pathway in rat vascular smooth muscle cells
X Pang, J Liu, J Zhao, J Mao, X Zhang, L Feng, C Han… - Atherosclerosis, 2014 - Elsevier
Abstract Objective Homocysteine (Hcy) is known as an independent risk factor for
atherosclerosis. C-reactive protein (CRP) directly participates in initiation and progression of …
atherosclerosis. C-reactive protein (CRP) directly participates in initiation and progression of …
The relationship between inflammation and venous thrombosis
EA Fox, SR Kahn - Thrombosis and haemostasis, 2005 - thieme-connect.com
During the past decade, the role of inflammation in the pathophysiology of arterial
thrombosis has been elucidated. However, comparatively little is known about the …
thrombosis has been elucidated. However, comparatively little is known about the …
C-reactive protein accelerates the progression of atherosclerosis in apolipoprotein E–deficient mice
Background—Plasma C-reactive protein (CRP) concentration is a strong predictor of
atherosclerosis. However, to date, there is no in vivo evidence that CRP is proatherogenic …
atherosclerosis. However, to date, there is no in vivo evidence that CRP is proatherogenic …
C-reactive protein and cardiovascular disease: new insights from an old molecule
GM Hirschfield, MB Pepys - Qjm, 2003 - academic.oup.com
The classical acute-phase protein, C-reactive protein (CRP), is an exquisitely sensitive
systemic marker of disease with broad clinical utility for monitoring and differential diagnosis …
systemic marker of disease with broad clinical utility for monitoring and differential diagnosis …
C-reactive protein is a mediator of cardiovascular disease
RJ Bisoendial, SM Boekholdt, M Vergeer… - European heart …, 2010 - academic.oup.com
C-reactive protein is postulated to embody an index that can reflect cardiovascular risk and
can be used to independently predict major cardiovascular events and mortality. On the …
can be used to independently predict major cardiovascular events and mortality. On the …
Contrasting Actions of Endothelin ETA and ETB Receptors in Cardiovascular Disease
MP Schneider, EI Boesen… - Annu. Rev. Pharmacol …, 2007 - annualreviews.org
First identified as a powerful vasoconstrictor, endothelin has an extremely diverse set of
actions that influence homeostatic mechanisms throughout the body. Two receptor subtypes …
actions that influence homeostatic mechanisms throughout the body. Two receptor subtypes …
Systemic inflammation in patients with COPD and pulmonary hypertension
P Joppa, D Petrasova, B Stancak, R Tkacova - Chest, 2006 - Elsevier
Study objectives COPD is a systemic disorder that is associated with increases of
inflammatory proteins in systemic circulation. However, no data on the potential role of …
inflammatory proteins in systemic circulation. However, no data on the potential role of …
Effects of fluticasone on systemic markers of inflammation in chronic obstructive pulmonary disease
Systemic inflammation is present in chronic obstructive pulmonary disease (COPD), which
has been linked to cardiovascular morbidity and mortality. We determined the effects of oral …
has been linked to cardiovascular morbidity and mortality. We determined the effects of oral …