Хроническая обструктивная болезнь легких (ХОБЛ) является одной из ведущих причин
заболеваемости и смертности в современном обществе и представ ляет собой …

Increased endothelin-1–mediated vasoconstrictor tone has been linked to the etiology of a
number of pathologies associated with human aging, including hypertension, congestive …

The systemic manifestations of chronic obstructive pulmonary disease (COPD)
exacerbations are recognized, but our understanding of their etiology and importance is …

Long-term arsenic exposure is associated with an increased risk of vascular diseases
including ischemic heart disease, cerebrovascular disease, and carotid atherosclerosis. The …

Recent advances in basic science have shown that atherosclerosis should be considered as
a chronic inflammatory process, and that a pivotal role of inflammation is evident from …

The endothelium plays a key role in vascular homeostasis through the release of a variety of
autocrine and paracrine substances, the best characterized being nitric oxide. A healthy …

Cardiovascular disease represents a considerable burden in terms of both morbidity and
mortality in patients with chronic obstructive pulmonary disease (COPD). For 20 years …

In humans, a chronically increased circulating level of C-reactive protein (CRP), a positive
acute-phase reactant, is an independent risk factor for cardiovascular disease. This …

Background—Circulating concentrations of the sensitive inflammatory marker C-reactive
protein (CRP) predict future cardiovascular events, and CRP is elevated during sepsis and …

2128 events between the upper and lower tertiles of hsCRP independent of clinical risk
assessment or lipid profiles. More recent updates that include a revised meta-analysis of 22 …