Scutellaria baicalensis Georgi., a plant used in traditional Chinese medicine, has multiple
biological activities, including anti-inflammatory, antiviral, antitumor, antioxidant, and …

There have been magnificent advancements in the understanding of molecular mechanisms
of chronic diseases over the past several years, but these diseases continue to be a …

Oxidative stress plays a major role in acute and chronic liver injury. In hepatocytes, oxidative
stress frequently triggers antioxidant response by activating nuclear erythroid 2‐related …

Inflammation and oxidative stress are essential for the pathogenesis of fulminant hepatic
failure (FHF). Asiatic acid (AA), which is a pentacyclic triterpene that widely occurs in various …

Acute liver injury (ALI) is a life-threatening syndrome accompanied by overwhelming
inflammation. Amygdalin (AGD) has been reported to possess various biological activities …

Background Acetaminophen (APAP) overdose-induced acute liver failure (ALF) is mainly
resulted from uncontrolled oxidative stress. Nuclear factor-erythroid 2-related factor 2 (Nrf2) …

Acute liver failure (ALF), an inflammation-mediated hepatocellular injury process, is a life-
threatening and fatal clinical syndrome. Daphnetin (Daph) has been reported to exhibit …

Background: Acute kidney injury (AKI) occurs in approximately 7–18% of all hospitalizations,
but there are currently no effective drug therapy for preventing AKI or delaying its …

Numerous studies have exemplified the importance of nuclear factor erythroid 2-related
factor 2 (Nrf2) activation in the alleviation of toxin-induced hepatic disorders primarily …

Oroxylin A, a natural flavonoid isolated from the medicinal herb Scutellaria baicalensis
Georgi, has been reported to have anti-inflammatory and antioxidant properties. However …