Global epidemiology of alcohol-associated cirrhosis and HCC: trends, projections and risk factors

DQ Huang, P Mathurin, H Cortez-Pinto… - Nature reviews …, 2023 - nature.com
Heavy alcohol consumption is a major cause of morbidity and mortality. Globally, alcohol per-
capita consumption rose from 5.5 litres in 2005 to 6.4 litres in 2016 and is projected to …

Molecular mechanisms and physiological functions of mitophagy

M Onishi, K Yamano, M Sato, N Matsuda… - The EMBO …, 2021 - embopress.org
Degradation of mitochondria via a selective form of autophagy, named mitophagy, is a
fundamental mechanism conserved from yeast to humans that regulates mitochondrial …

Contemporary epidemiology of chronic liver disease and cirrhosis

AM Moon, AG Singal, EB Tapper - Clinical Gastroenterology and …, 2020 - Elsevier
Background & Aims Accurate estimates for the contemporary burden of chronic liver disease
(CLD) are vital for setting clinical, research, and policy priorities. We aimed to review the …

[HTML][HTML] Epidemiology of non-alcoholic and alcoholic fatty liver diseases

S Mitra, A De, A Chowdhury - Translational gastroenterology and …, 2020 - ncbi.nlm.nih.gov
Liver diseases are fast emerging as global health priorities. Fatty liver is described in the
setting of non-alcoholic fatty liver disease (NAFLD) as well as alcoholic liver disease (ALD) …

[PDF][PDF] Diagnosis and treatment of alcohol‐associated liver diseases: 2019 practice guidance from the American Association for the Study of Liver Diseases

DW Crabb, GY Im, G Szabo, JL Mellinger… - Hepatology, 2020 - Wiley Online Library
Alcohol-associated liver disease (ALD) represents a spectrum of liver injury resulting from
alcohol use, ranging from hepatic steatosis to more advanced forms including alcoholic …

Burden of liver diseases in the world

SK Asrani, H Devarbhavi, J Eaton, PS Kamath - Journal of hepatology, 2019 - Elsevier
Liver disease accounts for approximately 2 million deaths per year worldwide, 1 million due
to complications of cirrhosis and 1 million due to viral hepatitis and hepatocellular …

Alcohol, liver disease and the gut microbiota

JS Bajaj - Nature Reviews Gastroenterology & Hepatology, 2019 - nature.com
Alcoholic liver disease, which ranges from mild disease to alcoholic hepatitis and cirrhosis,
is a leading cause of morbidity and mortality worldwide. Alcohol intake can lead to changes …

Mortality due to cirrhosis and liver cancer in the United States, 1999-2016: observational study

EB Tapper, ND Parikh - bmj, 2018 - bmj.com
Objective To describe liver disease related mortality in the United States during 1999-2016
by age group, sex, race, cause of liver disease, and geographic region. Design …

The relationship between different dimensions of alcohol use and the burden of disease—an update

J Rehm, GE Gmel Sr, G Gmel, OSM Hasan, S Imtiaz… - …, 2017 - Wiley Online Library
Background and aims Alcohol use is a major contributor to injuries, mortality and the burden
of disease. This review updates knowledge on risk relations between dimensions of alcohol …

Acetate reprograms gut microbiota during alcohol consumption

C Martino, LS Zaramela, B Gao, M Embree… - Nature …, 2022 - nature.com
Liver damage due to chronic alcohol use is among the most prevalent liver diseases.
Alcohol consumption frequency is a strong factor of microbiota variance. Here we use …