Addictions are often characterized as forms of impulsive behavior. That said, it is often noted
that impulsivity is a multidimensional construct, spanning several psychological domains …

The noradrenergic and cholinergic modulation of functionally distinct regions of the brain
has become one of the primary organizational principles behind understanding the …

The serotonin 5-HT2A receptor is the major target of psychedelic drugs such as lysergic acid
diethylamide (LSD), mescaline, and psilocybin. Serotonergic psychedelics induce profound …

Background: Binge drinking is prevalent during adolescence and may have effects on the
adult brain and behavior. The present study investigated whether adolescent intermittent …

Although smoking prevalence has declined in recent years, certain subpopulations continue
to smoke at disproportionately high rates and show resistance to cessation treatments …

Background: Cannabis (marijuana) is the most widely used illicit drug in the USA, and
consumption among adolescents is rising. Some animal studies show that adolescent …

Cholinergic neurotransmission affects decision-making, notably through the modulation of
perceptual processing in the cortex. In addition, acetylcholine acts on value-based decisions …

The ability to make advantageous decisions under circumstances in which there is a risk of
adverse consequences is an important component of adaptive behavior; however, extremes …

Impulsive choice, often characterized by excessive preference for small, short-term rewards
over larger, long-term rewards, is a prominent feature of substance use and other …

Rationale Catecholamine transmission modulates numerous cognitive and reward-related
processes that can subserve more complex functions such as cost/benefit decision making …