In tandem with recent progress in basic and clinical research in amyotrophic lateral sclerosis
(ALS), clinical care and management has improved substantially. Key processes and …

Sensorineural hearing loss, as a result of damage to or destruction of the sensory epithelia
within the cochlea, is a common cause of deafness. The subsequent degeneration of the …

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease where motor neurons
within the brain and spinal cord are lost, leading to paralysis and death. Certain growth …

Coordinated and constructive physical activity is correlated with the maintenance of
cognitive function in humans. Voluntary running also enhances neuroplasticity in adult and …

Objective: To assess and compare quality of life (QOL) for two groups of patients with
amyotrophic lateral sclerosis (ALS):(1) those reporting a more positive quality of life and (2) …

We have examined, as predictors of survival in patients with amyotrophic lateral sclerosis
(ALS), linear estimates of rates of disease progression (LEP), based on motor unit number …

Background: Besides its role in neuronal growth and differentiation, brain-derived
neurotrophic factor (BDNF) has been implicated in the control of peristalsis where it serves …

There is a vast amount of evidence indicating that neurotrophic factors play a major role in
the development, maintenance, and survival of neurons and neuron-supporting cells such …

Patients with amyotrophic lateral sclerosis (ALS) invariably develop respiratory muscle
weakness and most die from pulmonary complications. There are numerous tests available …

This study aimed to investigate whether continuous, low-dose, intracerebral infusion of
either brain-derived neurotrophic factor (BDNF) or neurotrophin-3 (NT-3) could protect …