A comprehensive review on chlorpyrifos toxicity with special reference to endocrine disruption: Evidence of mechanisms, exposures and mitigation strategies

HU ur Rahman, W Asghar, W Nazir, MA Sandhu… - Science of The Total …, 2021 - Elsevier
Chlorpyrifos (CPF) is a broad-spectrum chlorinated organophosphate (OP) pesticide used
for the control of a variety of insects and pathogens in crops, fruits, vegetables, as well as …

[HTML][HTML] Advanced approaches to breast cancer classification and diagnosis

M Zubair, S Wang, N Ali - Frontiers in Pharmacology, 2021 - frontiersin.org
The International Agency for Research on Cancer (IARC) has recently reported a 66%
increase in the global number of cancer deaths since 1960. In the US alone, about one in …

Nuclear receptors outside the nucleus: extranuclear signalling by steroid receptors

ER Levin, SR Hammes - Nature reviews Molecular cell biology, 2016 - nature.com
Steroid hormone receptors mediate numerous crucial biological processes and are
classically thought to function as transcriptional regulators in the nucleus. However, it has …

[图书][B] The China study: the most comprehensive study of nutrition ever conducted and the startling implications for diet, weight loss and long-term health

TM Campbell II - 2004 - books.google.com
Even today, as trendy diets and a weight-loss frenzy sweep the nation, two-thirds of adults
are still obese and children are being diagnosed with Type 2 diabetes, typically an “adult” …

Identity and dynamics of mammary stem cells during branching morphogenesis

CLGJ Scheele, E Hannezo, MJ Muraro, A Zomer… - Nature, 2017 - nature.com
During puberty, the mouse mammary gland develops into a highly branched epithelial
network. Owing to the absence of exclusive stem cell markers, the location, multiplicity …

Regulation of mammary gland branching morphogenesis by the extracellular matrix and its remodeling enzymes

JE Fata, Z Werb, MJ Bissell - Breast cancer research, 2003 - Springer
A considerable body of research indicates that mammary gland branching morphogenesis is
dependent, in part, on the extracellular matrix (ECM), ECM-receptors, such as integrins and …

Establishing a framework for the functional mammary gland: from endocrinology to morphology

RC Hovey, JF Trott, BK Vonderhaar - Journal of mammary gland biology …, 2002 - Springer
From its embryonic origins, the mammary gland in females undergoes a course of ductal
development that supports the establishment of alveolar structures during pregnancy prior to …

Pesticide chlorpyrifos acts as an endocrine disruptor in adult rats causing changes in mammary gland and hormonal balance

C Ventura, MRR Nieto, N Bourguignon… - The Journal of steroid …, 2016 - Elsevier
Endocrine disruptors (EDs) are compounds that interfere with hormone regulation and
influence mammary carcinogenesis. We have previously demonstrated that the pesticide …

[PDF][PDF] Serum levels of insulin-like growth factor system components and relationship to bone metabolism in type 1 and type 2 diabetes mellitus patients

PM Jehle, DR Jehle, S Mohan… - Journal of endocrinology, 1998 - researchgate.net
Osteopenia has been ascribed to diabetics without residual insulin secretion and high
insulin requirement. However, it is not known if this is partially due to disturbances in the IGF …

[HTML][HTML] The MAPKERK-1, 2 pathway integrates distinct and antagonistic signals from TGFα and FGF7 in morphogenesis of mouse mammary epithelium

JE Fata, H Mori, AJ Ewald, H Zhang, E Yao, Z Werb… - Developmental …, 2007 - Elsevier
Transforming growth factor-α (TGFα) and fibroblast growth factor-7 (FGF7) exhibit distinct
expression patterns in the mammary gland. Both factors signal through mitogen-activated …