Novel Insights into Aspergillus fumigatus Pathogenesis and Host Response from State-of-the-Art Imaging of Host–Pathogen Interactions during Infection
Aspergillus fumigatus spores initiate more than 3,000,000 chronic and 300,000 invasive
diseases annually, worldwide. Depending on the immune status of the host, inhalation of …
diseases annually, worldwide. Depending on the immune status of the host, inhalation of …
[HTML][HTML] Exploring the impact of fungal spores from agricultural environments on the mice lung microbiome and metabolic profile
B Wu, J Li, Y Wang, J Yang, Y Ye, J Sun… - Ecotoxicology and …, 2023 - Elsevier
Exposure to particulate matter (PM) from agricultural environments has been extensively
reported to cause respiratory health concerns in both animals and agricultural workers …
reported to cause respiratory health concerns in both animals and agricultural workers …
Characterization of Aspergillus fumigatus secretome during sublethal infection of Galleria mellonella larvae
A Curtis, P Dobes, J Marciniak… - Journal of Medical …, 2024 - microbiologyresearch.org
Introduction. The fungal pathogen Aspergillus fumigatus can induce prolonged colonization
of the lungs of susceptible patients, resulting in conditions such as allergic …
of the lungs of susceptible patients, resulting in conditions such as allergic …
Distinct Cohorts of Aspergillus fumigatus Transcription Factors Are Required for Epithelial Damage Occurring via Contact- or Soluble Effector-Mediated Mechanisms
S Rahman, N van Rhijn, P Papastamoulis… - Frontiers in cellular …, 2022 - frontiersin.org
Damage to the lung epithelium is a unifying feature of disease caused by the saprophytic
fungus Aspergillus fumigatus. However, the mechanistic basis and the regulatory control of …
fungus Aspergillus fumigatus. However, the mechanistic basis and the regulatory control of …
A series of pyrimidine-based antifungals with anti-mold activity disrupt ER function in Aspergillus fumigatus
MT Kelty, A Miron-Ocampo, SR Beattie - Microbiology spectrum, 2024 - Am Soc Microbiol
Fungal infections are a major contributor to morbidity and mortality among
immunocompromised populations. Moreover, fungal disease caused by molds are difficult to …
immunocompromised populations. Moreover, fungal disease caused by molds are difficult to …
Epithelial uptake of Aspergillus fumigatus drives efficient fungal clearance in vivo and is aberrant in Chronic Obstructive Pulmonary Disease (COPD)
M Bertuzzi, GJ Howell, DD Thomson, R Fortune-Grant… - bioRxiv, 2022 - biorxiv.org
Hundreds of spores of the common mould A spergillus f umigatus (Af) are inhaled daily by
human beings, representing a constant, often fatal, threat to our respiratory health. The small …
human beings, representing a constant, often fatal, threat to our respiratory health. The small …
Epithelial uptake leads to fungal killing in vivo and is aberrant in COPD-derived epithelial cells
M Bertuzzi, GJ Howell, DD Thomson, R Fortune-Grant… - Iscience, 2024 - cell.com
Hundreds of spores of Aspergillus fumigatus (Af) are inhaled daily by human beings,
representing a constant, possibly fatal, threat to respiratory health. The small size of Af …
representing a constant, possibly fatal, threat to respiratory health. The small size of Af …
Evaluation of interleukin-8 levels in the diagnosis of invasive pulmonary aspergillosis in patients with haematological malignancies
L Şensoy, A Atilla, YT Güllü, D Gür Vural… - Medical …, 2024 - academic.oup.com
This study aimed to determine the level of interleukin (IL)-8 in diagnosing of invasive
pulmonary aspergillosis (IPA). We conducted this study with 50 controls and 25 IPA patients …
pulmonary aspergillosis (IPA). We conducted this study with 50 controls and 25 IPA patients …