BAK contributes critically to necrosis and infarct generation during reperfused myocardial infarction
At least seven cell death programs are activated during myocardial infarction (MI), but which
are most important in causing heart damage is not understood. Two of these programs are …
are most important in causing heart damage is not understood. Two of these programs are …
The systemic deletion of interleukin-1α reduces myocardial inflammation and attenuates ventricular remodeling in murine myocardial infarction
Myocardial inflammation following myocardial infarction (MI) is crucial for proper myocardial
healing, yet, dysregulated inflammation may promote adverse ventricular remodeling and …
healing, yet, dysregulated inflammation may promote adverse ventricular remodeling and …
Standardisation and future of preclinical echocardiography
CE O'Riordan, P Trochet, M Steiner, D Fuchs - Mammalian Genome, 2023 - Springer
Echocardiography is a non-invasive imaging technique providing real-time information to
assess the structure and function of the heart. Due to advancements in technology, ultra …
assess the structure and function of the heart. Due to advancements in technology, ultra …
[HTML][HTML] Localized strain characterization of cardiomyopathy in Duchenne muscular dystrophy using novel 4D kinematic analysis of cine cardiovascular magnetic …
CC Earl, VI Pyle, SQ Clark, K Annamalai… - Journal of …, 2023 - Elsevier
Background Cardiomyopathy (CMP) is the most common cause of mortality in Duchenne
muscular dystrophy (DMD), though the age of onset and clinical progression vary. We …
muscular dystrophy (DMD), though the age of onset and clinical progression vary. We …
Neurovascular hypoxia after mild traumatic brain injury in juvenile mice correlates with heart–brain dysfunctions in adulthood
Aim Retrospective studies suggest that mild traumatic brain injury (mTBI) in pediatric
patients may lead to an increased risk of cardiac events. However, the exact functional and …
patients may lead to an increased risk of cardiac events. However, the exact functional and …
[HTML][HTML] PPARγ Agonist Pioglitazone Prevents Hypoxia-induced Cardiac Dysfunction by Reprogramming Glucose Metabolism
Y Wang, R Zhang, Q Chen, Z Lei, C Shi… - … Journal of Biological …, 2024 - ncbi.nlm.nih.gov
The heart relies on various defense mechanisms, including metabolic plasticity, to maintain
its normal structure and function under high-altitude hypoxia. Pioglitazone, a peroxisome …
its normal structure and function under high-altitude hypoxia. Pioglitazone, a peroxisome …
[HTML][HTML] Postnatally overfed mice display cardiac function alteration following myocardial infarction
M Josse, E Rigal, N Rosenblatt-Velin, B Collin… - … et Biophysica Acta (BBA …, 2024 - Elsevier
Background Cardiovascular (CV) pathologies remain a leading cause of death worldwide,
often associated with common comorbidities such as overweight, obesity, type 2 diabetes or …
often associated with common comorbidities such as overweight, obesity, type 2 diabetes or …
4D ultrasound‐based strain assessment of cardiac dysfunction in male rats with reperfused and nonreperfused myocardial infarction
Abstract Two‐dimensional ultrasound (2DUS) echocardiography is the main noninvasive
method used to evaluate cardiac function in animal models of myocardial infarction (MI) …
method used to evaluate cardiac function in animal models of myocardial infarction (MI) …
High-resolution cardiac positron emission tomography/computed tomography for small animals
Positron emission tomography (PET) and computed tomography (CT) are among the most
employed diagnostic imaging techniques, and both serve in understanding cardiac function …
employed diagnostic imaging techniques, and both serve in understanding cardiac function …
[HTML][HTML] Functional cardiac consequences of β-adrenergic stress-induced injury in the mdx mouse model of Duchenne muscular dystrophy
CC Earl, AJ Javier, AM Richards, LW Markham… - bioRxiv, 2024 - ncbi.nlm.nih.gov
Cardiomyopathy is the leading cause of death in Duchenne muscular dystrophy (DMD),
however, in the mdx mouse model of DMD, the cardiac phenotype differs from that seen in …
however, in the mdx mouse model of DMD, the cardiac phenotype differs from that seen in …