Alternative splicing (AS) serves as a pivotal mechanism in transcriptional regulation,
engendering transcript diversity, and modifications in protein structure and functionality …

Programmed cell death is an active extinction process, including autophagy, ferroptosis,
pyroptosis, apoptosis, and necroptosis. m6A is a reversible RNA modification which …

Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are fatal
neurodegenerative disorders on a disease spectrum that are characterized by the …

Heterogeneous nuclear ribonucleoprotein C (HNRNPC) is an essential, ubiquitously
abundant protein involved in mRNA processing. Genetic variants in other members of the …

Tau protein is a known contributor in several neurodegenerative diseases, including
Alzheimer's disease (AD) and frontotemporal dementia (FTD). It is well-established that tau …

DNA double-strand breaks (DSBs) are highly cytotoxic DNA lesions. To protect genomic
stability and ensure cell homeostasis, cells mount a complex signaling-based response that …

Heterogeneous nuclear ribonucleoprotein A/B (hnRNPA/B) is one of the core members of
the RNA binding protein (RBP) hnRNPs family, including four main subtypes, A0, A1, A2/B1 …

Autoimmune diseases (ADs) are chronic pathologies generated by the loss of immune
tolerance to the body's own cells and tissues. There is growing recognition that RNA …

Background & Aims Cancer stemness and immune evasion are closely associated and play
critical roles in tumor development and resistance to immunotherapy. However, little is …

Rheumatoid arthritis (RA) is a multifaceted autoimmune disease characterized by systemic
inflammation, affecting both articular and extra-articular structures. This condition results in …