Drug toxicity evaluation is an essential process of drug development as it is reportedly
responsible for the attrition of approximately 30% of drug candidates. The rapid increase in …

The existence of polycyclic aromatic hydrocarbons (PAHs) in ambient air is an escalating
concern worldwide because of their ability to cause cancer and induce permanent changes …

The human genome is 'pervasively transcribed'leading to a complex array of non-coding
RNAs (ncRNAs) that far outnumber coding mRNAs. ncRNAs have regulatory roles in …

Long non-coding RNAs (lncRNAs) are over 200 nucleotides in length and are transcribed
from the mammalian genome in a tissue-specific and developmentally regulated pattern …

Abstract MicroRNAs (miRNAs) are short (22 nucleotides), single-stranded, non-coding
RNAs that form complimentary base-pairs with the 3′ untranslated region of target mRNAs …

Environmental exposures to hazardous chemicals are associated with a variety of human
diseases and disorders, including cancers. Phase I metabolic activation and detoxification …

Ammonia (NH 3) is one of major air pollutants in intensive poultry houses, affecting chicken
health. Circular RNA (circRNA) is a novel type of RNA that can regulate gene expression …

Biomarker measurements that reliably correlate with tissue injury and that can be measured
within accessible biofluids offer benefits in terms of cost, time, and convenience when …

Abstract microRNAs (miRNAs or miRs) are short non-coding RNA molecules which have
been shown to be dysregulated and released into the extracellular milieu as a result of many …

Abstract Fine particulate matter (PM2. 5) exposure, especially to its organic components,
induces adverse health effects on the respiratory system. However, the molecular …