The pathogenesis of Parkinson's disease: a complex interplay between astrocytes, microglia, and T lymphocytes?

AN MacMahon Copas, SF McComish… - Frontiers in …, 2021 - frontiersin.org
Parkinson's disease (PD), the second most common neurodegenerative disease, is
characterised by the motor symptoms of bradykinesia, rigidity and resting tremor and non …

A systematic review of the applications of artificial intelligence and machine learning in autoimmune diseases

IS Stafford, M Kellermann, E Mossotto, RM Beattie… - NPJ digital …, 2020 - nature.com
Autoimmune diseases are chronic, multifactorial conditions. Through machine learning (ML),
a branch of the wider field of artificial intelligence, it is possible to extract patterns within …

Severe Neuro-COVID is associated with peripheral immune signatures, autoimmunity and neurodegeneration: a prospective cross-sectional study

MM Etter, TA Martins, L Kulsvehagen… - Nature …, 2022 - nature.com
Growing evidence links COVID-19 with acute and long-term neurological dysfunction.
However, the pathophysiological mechanisms resulting in central nervous system …

IL-17 family: cytokines, receptors and signaling

C Gu, L Wu, X Li - Cytokine, 2013 - Elsevier
Abstract The interleukin 17 (IL-17) family, a subset of cytokines consisting of IL-17A–F, plays
crucial roles in host defense against microbial organisms and in the development of …

The activation and regulation of IL-17 receptor mediated signaling

X Song, Y Qian - Cytokine, 2013 - Elsevier
Interleukin-17 (IL-17), the signature cytokine produced by T helper 17 (Th17) cells, plays
pivotal roles in host defense responses against microbial invasion, as well as in the …

A potential link between environmental triggers and autoimmunity

A Vojdani - Autoimmune diseases, 2014 - Wiley Online Library
Autoimmune diseases have registered an alarming rise worldwide in recent years.
Accumulated evidence indicates that the immune system′ s ability to distinguish self from …

Immunomodulatory molecules of Fasciola hepatica: candidates for both vaccine and immunotherapeutic development

JP Dalton, MW Robinson, G Mulcahy, SM O'Neill… - Veterinary …, 2013 - Elsevier
The liver fluke, Fasciola hepatica, causes fascioliasis in domestic animals (sheep, cattle), a
global disease that is also an important infection of humans. As soon as the parasite invades …

[HTML][HTML] Temporal and spatial interplay of microbiota and intestinal mucosa drive establishment of immune homeostasis in conventionalized mice

S El Aidy, P Van Baarlen, M Derrien… - Mucosal …, 2012 - Elsevier
During colonization of germfree mice with the total fecal microbial community of their
conventionally born and raised siblings (conventionalization), the intestinal mucosal …

The effect of martial arts training on mental health outcomes: A systematic review and meta-analysis

B Moore, D Dudley, S Woodcock - Journal of bodywork and movement …, 2020 - Elsevier
Objective Mental health issues are of increasing public concern, however are often
untreated for a variety of reasons. While limited, the research examining the relationship …

Glucocorticoids, cyclosporine, azathioprine, chlorambucil, and mycophenolate in dogs and cats: clinical uses, pharmacology, and side effects

KR Viviano - Veterinary Clinics: Small Animal Practice, 2022 - vetsmall.theclinics.com
The body's immune system is essential for protecting it from various pathogens and other
external insults. The immune system is tightly regulated and maintained through the …