[HTML][HTML] Local and systemic mechanisms linking periodontal disease and inflammatory comorbidities

G Hajishengallis, T Chavakis - Nature Reviews Immunology, 2021 - nature.com
Periodontitis, a major inflammatory disease of the oral mucosa, is epidemiologically
associated with other chronic inflammation-driven disorders, including cardio-metabolic …

Interconnection of periodontal disease and comorbidities: Evidence, mechanisms, and implications

G Hajishengallis - Periodontology 2000, 2022 - Wiley Online Library
Periodontitis, a microbiome‐driven inflammatory disease of the tooth‐attachment apparatus,
is epidemiologically linked with other disorders, including cardio‐metabolic, cognitive …

Association between periodontitis and severity of COVID‐19 infection: A case–control study

N Marouf, W Cai, KN Said, H Daas… - Journal of clinical …, 2021 - Wiley Online Library
Aim COVID‐19 is associated with an exacerbated inflammatory response that can result in
fatal outcomes. Systemic inflammation is also a main characteristic of periodontitis …

Mechanisms underlying the association between periodontitis and atherosclerotic disease

HA Schenkein, PN Papapanou, R Genco… - Periodontology …, 2020 - Wiley Online Library
Atherosclerosis is central to the pathology of cardiovascular diseases, a group of diseases in
which arteries become occluded with atheromas that may rupture, leading to different …

[HTML][HTML] Periodontitis: a multifaceted disease of tooth-supporting tissues

E Könönen, M Gursoy, UK Gursoy - Journal of clinical medicine, 2019 - mdpi.com
Periodontitis is an infection-driven inflammatory disease in which the composition of biofilms
plays a significant role. Dental plaque accumulation at the gingival margin initiates an …

[HTML][HTML] Periodontal disease: a risk factor for diabetes and cardiovascular disease

D Liccardo, A Cannavo, G Spagnuolo… - International journal of …, 2019 - mdpi.com
Periodontitis is a chronic inflammatory disease, initiated by the presence of a bacterial
biofilm, called dental plaque, which affects both the periodontal ligaments and bone …

Periodontitis and implant complications in diabetes

L Nibali, N Gkranias, G Mainas… - Periodontology 2000, 2022 - Wiley Online Library
Epidemiologic evidence indicates that periodontitis is more frequent in patients with
uncontrolled diabetes mellitus than in healthy controls, suggesting that it could be …

Systemic effects of periodontitis treatment in patients with type 2 diabetes: a 12 month, single-centre, investigator-masked, randomised trial

F D'Aiuto, N Gkranias, D Bhowruth, T Khan… - The lancet Diabetes & …, 2018 - thelancet.com
Background Chronic inflammation is believed to be a major mechanism underlying the
pathophysiology of type 2 diabetes. Periodontitis is a cause of systemic inflammation. We …

Periodontitis, edentulism, and risk of mortality: a systematic review with meta-analyses

M Romandini, G Baima, G Antonoglou… - Journal of dental …, 2021 - journals.sagepub.com
Periodontitis has been independently associated with the chronic noncommunicable
diseases that most frequently lead to death worldwide. The aim of the present systematic …

Nonsurgical and surgical treatment of periodontitis: how many options for one disease?

F Graziani, D Karapetsa, B Alonso… - Periodontology …, 2017 - Wiley Online Library
Abstract Treatment of periodontitis aims at preventing further disease progression with the
intentions to reduce the risk of tooth loss, minimize symptoms and perception of the disease …