Type 1 neurofibromatosis gene: identification of a large transcript disrupted in three NF1 patients

MR Wallace, DA Marchuk, LB Andersen, R Letcher… - Science, 1990 - science.org
Von Recklinghausen neurofibromatosis (NF1) is a common autosomal dominant disorder
characterized by abnormalities in multiple tissues derived from the neural crest. No reliable …

The graft-versus-leukemia effects of allogeneic cell therapy

DL Porter, MD, JH Antin, MD - Annual review of medicine, 1999 - annualreviews.org
Until recently, the only cure for relapse after allogeneic bone marrow transplantation (BMT)
has been a second BMT. Recently, infusions of leukocytes collected from the original …

Sensitive detection of occult breast cancer by the reverse-transcriptase polymerase chain reaction.

YH Datta, PT Adams, WR Drobyski… - Journal of Clinical …, 1994 - ascopubs.org
PURPOSE Detection of occult carcinoma in patients with breast cancer may aid the
establishment of prognosis and development of new therapeutic approaches. To improve on …

Salvage immunotherapy using donor leukocyte infusions as treatment for relapsed chronic myelogenous leukemia after allogeneic bone marrow transplantation …

WR Drobyski, CA Keever, MS Roth, S Koethe… - 1993 - ashpublications.org
Eight patients who had hematologic relapse of chronic myelogenous leukemia (CML) after
undergoing allogeneic bone marrow transplantation (BMT) were treated with leukocyte …

Graft-versus-host disease and graft-versus-leukemia after donor leukocyte infusion

D Porter, JE Levine - Seminars in hematology, 2006 - Elsevier
Although dramatically effective for relapsed chronic myelogenous leukemia (CML),
successful donor leukocyte infusion (DLI) remains limited primarily by inadequate responses …

[HTML][HTML] Detection of residual leukemia after bone marrow transplant for chronic myeloid leukemia: role of polymerase chain reaction in predicting relapse

TP Hughes, GJ Morgan, P Martiat, JM Goldman - Blood, 1991 - Elsevier
We used the polymerase chain reaction (PCR) to detect residual leukemia-specific mRNA in
blood and marrow from 37 patients in complete hematologic and cytogenetic remission after …

[HTML][HTML] Detection of minimal residual disease in acute promyelocytic leukemia by a reverse transcription polymerase chain reaction assay for the PML/RAR-α fusion …

WH Miller Jr, K Levine, A DeBlasio, SR Frankel… - Blood, 1993 - Elsevier
The characteristic reciprocal translocation t (15; 17) of acute promyelocytic leukemia (APL)
disrupts the PML gene on chromosome 15 and the retinoic acid receptor-α (RAR-α) gene on …

[PDF][PDF] Graft-versus-leukemia: no longer an epiphenomenon

JH Antin - BLOOD-NEW YORK-, 1993 - researchgate.net
HE PRINCIPLE that the transplant conditioning regi-T men might be inadequate to
completely eradicate leukemic hematopoiesis and that the antileukemic effect of infused …

Low specificity of cytokeratin 19 reverse transcriptase-polymerase chain reaction analyses for detection of hematogenous lung cancer dissemination.

M Krismann, B Todt, J Schröder, D Gareis… - Journal of clinical …, 1995 - ascopubs.org
PURPOSE Sensitive detection of systemic tumor dissemination in lung cancer patients is
important for selection of appropriate treatment modalities. Based on recent promising data …

Identification of bone marrow micrometastases in patients with prostate cancer

DP Wood Jr, ER Banks, S Humphreys, JW McRoberts… - Cancer, 1994 - Wiley Online Library
Background. Thirty percent of patients with clinically localized prostate cancer and a
negative bone scan will experience relapse with recurrent disease despite treatment of the …