The physics of functional magnetic resonance imaging (fMRI)

RB Buxton - Reports on Progress in Physics, 2013 - iopscience.iop.org
Functional magnetic resonance imaging (fMRI) is a methodology for detecting dynamic
patterns of activity in the working human brain. Although the initial discoveries that led to …

Non-BOLD contrast for laminar fMRI in humans: CBF, CBV, and CMRO2

L Huber, K Uludağ, HE Möller - Neuroimage, 2019 - Elsevier
Functional magnetic resonance imaging (fMRI) using the blood oxygenation level-
dependent (BOLD) contrast indirectly probes neuronal activity changes via evoked cerebral …

Cerebral oxygen extraction fraction MRI: Techniques and applications

D Jiang, H Lu - Magnetic resonance in medicine, 2022 - Wiley Online Library
The human brain constitutes 2% of the body's total mass but uses 20% of the oxygen. The
rate of the brain's oxygen utilization can be derived from a knowledge of cerebral blood flow …

Advanced MRI techniques to improve our understanding of experience-induced neuroplasticity

CL Tardif, CJ Gauthier, CJ Steele, PL Bazin, A Schäfer… - Neuroimage, 2016 - Elsevier
Over the last two decades, numerous human MRI studies of neuroplasticity have shown
compelling evidence for extensive and rapid experience-induced brain plasticity in vivo. To …

BOLD signal physiology: models and applications

CJ Gauthier, AP Fan - Neuroimage, 2019 - Elsevier
The BOLD contrast mechanism has a complex relationship with functional brain activity,
oxygen metabolism, and neurovascular factors. Accurate interpretation of the BOLD signal …

Age dependence of hemodynamic response characteristics in human functional magnetic resonance imaging

CJ Gauthier, C Madjar, L Desjardins-Crépeau… - Neurobiology of …, 2013 - Elsevier
Functional magnetic resonance imaging (fMRI) studies of cognitive aging have generally
compared the amplitude and extent of blood oxygen level-dependent (BOLD) signal …

[HTML][HTML] Age differences in brain signal variability are robust to multiple vascular controls

DD Garrett, U Lindenberger, RD Hoge, CJ Gauthier - Scientific reports, 2017 - nature.com
A host of studies support that younger, better performing adults express greater moment-to-
moment blood oxygen level-dependent (BOLD) signal variability (SDBOLD) in various …

Calibrated fMRI

RD Hoge - Neuroimage, 2012 - Elsevier
Functional magnetic resonance imaging with blood oxygenation level-dependent (BOLD)
contrast has had a tremendous influence on human neuroscience in the last twenty years …

A neural-vascular complex of age-related changes in the human brain: Anatomy, physiology, and implications for neurocognitive aging

D Abdelkarim, Y Zhao, MP Turner… - Neuroscience & …, 2019 - Elsevier
Theories of neurocognitive aging rely heavily on functional magnetic resonance imaging
(fMRI) to test hypotheses regarding the brain basis of age-differences in cognition. This …

[HTML][HTML] The role of cerebrovascular-reactivity mapping in functional MRI: calibrated fMRI and resting-state fMRI

JJ Chen, CJ Gauthier - Frontiers in physiology, 2021 - frontiersin.org
Task and resting-state functional MRI (fMRI) is primarily based on the same blood-
oxygenation level-dependent (BOLD) phenomenon that MRI-based cerebrovascular …