Comparison of CO2 in Air Versus Carbogen for the Measurement of Cerebrovascular Reactivity with Magnetic Resonance Imaging

HV Hare, M Germuska, ME Kelly… - Journal of Cerebral …, 2013 - journals.sagepub.com
Measurement of cerebrovascular reactivity (CVR) can give valuable information about
existing pathology and the risk of adverse events, such as stroke. A common method of …

[HTML][HTML] Sources of systematic error in calibrated BOLD based mapping of baseline oxygen extraction fraction

NP Blockley, VEM Griffeth, AJ Stone, HV Hare… - Neuroimage, 2015 - Elsevier
Recently a new class of calibrated blood oxygen level dependent (BOLD) functional
magnetic resonance imaging (MRI) methods were introduced to quantitatively measure the …

Brain metabolism in tau and amyloid mouse models of Alzheimer's disease: An MRI study

Z Wei, J Xu, L Chen, L Hirschler, EL Barbier… - NMR in …, 2021 - Wiley Online Library
Alzheimer's disease (AD) is the leading cause of cognitive impairment and dementia in
elderly individuals. According to the current biomarker framework for “unbiased descriptive …

[HTML][HTML] Multi-modal normalization of resting-state using local physiology reduces changes in functional connectivity patterns observed in mTBI patients

AA Champagne, NS Coverdale, A Ross, Y Chen… - NeuroImage: Clinical, 2020 - Elsevier
Blood oxygenation level dependent (BOLD) resting-state functional magnetic resonance
imaging (rs-fMRI) may serve as a sensitive marker to identify possible changes in the …

[HTML][HTML] The potential for gas-free measurements of absolute oxygen metabolism during both baseline and activation states in the human brain

EY Liu, J Guo, AB Simon, F Haist, DJ Dubowitz… - Neuroimage, 2020 - Elsevier
Quantitative functional magnetic resonance imaging methods make it possible to measure
cerebral oxygen metabolism (CMRO 2) in the human brain. Current methods require the …

A BOLD perspective on age-related neurometabolic-flow coupling and neural efficiency changes in human visual cortex

JL Hutchison, E Shokri-Kojori, H Lu… - Frontiers in …, 2013 - frontiersin.org
Age-related performance declines in visual tasks have been attributed to reductions in
processing efficiency. The neural basis of these declines has been explored by comparing …

[HTML][HTML] Cerebral oxygen metabolism from MRI susceptibility

E Biondetti, J Cho, H Lee - Neuroimage, 2023 - Elsevier
This article provides an overview of MRI methods exploiting magnetic susceptibility
properties of blood to assess cerebral oxygen metabolism, including the tissue oxygen …

[HTML][HTML] Assessing the repeatability of absolute CMRO2, OEF and haemodynamic measurements from calibrated fMRI

A Merola, MA Germuska, K Murphy, RG Wise - Neuroimage, 2018 - Elsevier
As energy metabolism in the brain is largely oxidative, the measurement of cerebral
metabolic rate of oxygen consumption (CMRO 2) is a desirable biomarker for quantifying …

A non-invasive reference-based method for imaging the cerebral metabolic rate of oxygen by PET/MR: theory and error analysis

L Narciso, T Ssali, H Iida… - Physics in Medicine & …, 2021 - iopscience.iop.org
Positron emission tomography (PET) remains the gold standard for quantitative imaging of
the cerebral metabolic rate of oxygen (CMRO 2); however, it is an invasive and complex …

Laminar differences in functional oxygen metabolism in monkey visual cortex measured with calibrated fMRI

Y Bohraus, H Merkle, NK Logothetis, J Goense - Cell Reports, 2023 - cell.com
Blood-oxygenation-level-dependent functional magnetic resonance imaging (BOLD fMRI) of
cortical layers relies on the hemodynamic response and is biased toward large veins on the …