[HTML][HTML] Antibodies to combat viral infections: development strategies and progress
G Pantaleo, B Correia, C Fenwick, VS Joo… - Nature Reviews Drug …, 2022 - nature.com
Monoclonal antibodies (mAbs) are appealing as potential therapeutics and prophylactics for
viral infections owing to characteristics such as their high specificity and their ability to …
viral infections owing to characteristics such as their high specificity and their ability to …
Flavonoids target human herpesviruses that infect the nervous system: Mechanisms of action and therapeutic insights
M Šudomová, K Berchová-Bímová, A Mazurakova… - Viruses, 2022 - mdpi.com
Human herpesviruses (HHVs) are large DNA viruses with highly infectious characteristics.
HHVs can induce lytic and latent infections in their host, and most of these viruses are …
HHVs can induce lytic and latent infections in their host, and most of these viruses are …
40 Years after the Registration of Acyclovir: Do We Need New Anti-Herpetic Drugs?
A Majewska, B Mlynarczyk-Bonikowska - International journal of …, 2022 - mdpi.com
Herpes simplex virus types 1 and 2 HSV1 and 2, namely varicella-zoster VZV and
cytomegalovirus CMV, are among the most common pathogens worldwide. They remain in …
cytomegalovirus CMV, are among the most common pathogens worldwide. They remain in …
ChAdOx1‐S adenoviral vector vaccine applied intranasally elicits superior mucosal immunity compared to the intramuscular route of vaccination
M Cokarić Brdovčak, J Materljan… - European Journal of …, 2022 - Wiley Online Library
COVID‐19 vaccines prevent severe forms of the disease, but do not warrant complete
protection against breakthrough infections. This could be due to suboptimal mucosal …
protection against breakthrough infections. This could be due to suboptimal mucosal …
Chitosan/benzyloxy-benzaldehyde modified ZnO nano template having optimized and distinct antiviral potency to human cytomegalovirus
Utilization of biomolecules encapsulated nano particles is currently originating ample
attention to generate unconventional nanomedicines in antiviral research. Zinc oxide …
attention to generate unconventional nanomedicines in antiviral research. Zinc oxide …
Well Put Together—A Guide to Accessorizing with the Herpesvirus gH/gL Complexes
GL Gonzalez-Del Pino, EE Heldwein - Viruses, 2022 - mdpi.com
Herpesviruses are enveloped, double-stranded DNA viruses that infect a variety of hosts
across the animal kingdom. Nine of these establish lifelong infections in humans, for which …
across the animal kingdom. Nine of these establish lifelong infections in humans, for which …
Emerging concepts in congenital cytomegalovirus
MH Pesch, MR Schleiss - Pediatrics, 2022 - publications.aap.org
Over a century of research has focused on improving our understanding of congenital
cytomegalovirus (cCMV), yet it remains the most common congenital infection in the United …
cytomegalovirus (cCMV), yet it remains the most common congenital infection in the United …
[HTML][HTML] Differences in RNA polymerase II complexes and their interactions with surrounding chromatin on human and cytomegalovirus genomes
Interactions of the RNA polymerase II (Pol II) preinitiation complex (PIC) and paused early
elongation complexes with the first downstream (+ 1) nucleosome are thought to be …
elongation complexes with the first downstream (+ 1) nucleosome are thought to be …
[HTML][HTML] The cytomegalovirus gB/MF59 vaccine candidate induces antibodies against an antigenic domain controlling cell-to-cell spread
AC Gomes, IA Baraniak, A Lankina, Z Moulder… - Nature …, 2023 - nature.com
Vaccination against human cytomegalovirus (CMV) infection remains high priority. A
recombinant form of a protein essential for CMV entry, glycoprotein B (gB), demonstrated …
recombinant form of a protein essential for CMV entry, glycoprotein B (gB), demonstrated …
Roles of infection in psoriasis
S Zhou, Z Yao - International Journal of Molecular Sciences, 2022 - mdpi.com
Psoriasis is a chronic, immune-mediated disorder with cutaneous and systemic
manifestations. Genetic predisposition, environmental factors, and immune dysfunction all …
manifestations. Genetic predisposition, environmental factors, and immune dysfunction all …