Antibodies to combat viral infections: development strategies and progress
G Pantaleo, B Correia, C Fenwick, VS Joo… - Nature Reviews Drug …, 2022 - nature.com
Monoclonal antibodies (mAbs) are appealing as potential therapeutics and prophylactics for
viral infections owing to characteristics such as their high specificity and their ability to …
viral infections owing to characteristics such as their high specificity and their ability to …
mRNA vaccines: The future of prevention of viral infections?
P Rzymski, A Szuster‐Ciesielska… - Journal of medical …, 2023 - Wiley Online Library
Messenger RNA (mRNA) vaccines against COVID‐19 are the first authorized biological
preparations developed using this platform. During the pandemic, their administration has …
preparations developed using this platform. During the pandemic, their administration has …
Cytotoxic CD4+ T cells eliminate senescent cells by targeting cytomegalovirus antigen
Senescent cell accumulation has been implicated in the pathogenesis of aging-associated
diseases, including cancer. The mechanism that prevents the accumulation of senescent …
diseases, including cancer. The mechanism that prevents the accumulation of senescent …
40 years after the registration of acyclovir: do we need new anti-herpetic drugs?
A Majewska, B Mlynarczyk-Bonikowska - International journal of …, 2022 - mdpi.com
Herpes simplex virus types 1 and 2 HSV1 and 2, namely varicella-zoster VZV and
cytomegalovirus CMV, are among the most common pathogens worldwide. They remain in …
cytomegalovirus CMV, are among the most common pathogens worldwide. They remain in …
Intercellular communication within the virus microenvironment affects the susceptibility of cells to secondary viral infections
Communication between infected cells and cells in the surrounding tissue is a determinant
of viral spread. However, it remains unclear how cells in close or distant proximity to an …
of viral spread. However, it remains unclear how cells in close or distant proximity to an …
Emerging concepts in congenital cytomegalovirus
MH Pesch, MR Schleiss - Pediatrics, 2022 - publications.aap.org
Over a century of research has focused on improving our understanding of congenital
cytomegalovirus (cCMV), yet it remains the most common congenital infection in the United …
cytomegalovirus (cCMV), yet it remains the most common congenital infection in the United …
M‐CSF directs myeloid and NK cell differentiation to protect from CMV after hematopoietic cell transplantation
PK Kandalla, J Subburayalu, C Cocita… - EMBO Molecular …, 2023 - embopress.org
Therapies reconstituting autologous antiviral immunocompetence may represent an
important prophylaxis and treatment for immunosuppressed individuals. Following …
important prophylaxis and treatment for immunosuppressed individuals. Following …
Single-cell analysis of memory B cells from top neutralizers reveals multiple sites of vulnerability within HCMV Trimer and Pentamer
M Zehner, M Alt, A Ashurov, JA Goldsmith, R Spies… - Immunity, 2023 - cell.com
Human cytomegalovirus (HCMV) can cause severe diseases in fetuses, newborns, and
immunocompromised individuals. Currently, no vaccines are approved, and treatment …
immunocompromised individuals. Currently, no vaccines are approved, and treatment …
Congenital cytomegalovirus and hearing loss: The state of the art
M Aldè, S Binda, V Primache, L Pellegrinelli… - Journal of Clinical …, 2023 - mdpi.com
In developed countries, congenital cytomegalovirus (cCMV) infection is the most common
congenital viral infection, representing the leading non-genetic cause of sensorineural …
congenital viral infection, representing the leading non-genetic cause of sensorineural …
Cytomegalovirus in the transplant setting: Where are we now and what happens next? A report from the International CMV Symposium 2021
CN Kotton, J Torre‐Cisneros… - Transplant Infectious …, 2022 - Wiley Online Library
Abstract The CMV Symposium in September 2021 was an international conference
dedicated to cytomegalovirus (CMV) infection after solid organ or hematopoietic stem cell …
dedicated to cytomegalovirus (CMV) infection after solid organ or hematopoietic stem cell …