Background. Several studies have reported that statins have anti-inflammatory effects.
Nevertheless, results of clinical trials concerning the effect of statins on the levels of C …

Combining existing drug therapy is essential in developing new therapeutic agents in
disease prevention and treatment. In preclinical investigations, combined effect of certain …

Simple Summary Osteosarcoma is the most common form of primary solid bone malignancy,
with the highest incidence in adolescence. The therapeutic management includes surgical …

Background Benefits of elevated high-density lipoprotein cholesterol (HDL-C) levels are
challenged by reports demonstrating U-shaped relations between HDL-C levels and all …

Simple Summary Uveal melanoma is a rare and aggressive disease. Gα-proteins GNAQ
and GNA11 are driver mutations that activate MAP kinase and YAP/TAZ pathways. BAP1 …

Background Previous studies have reported that statin or ezetimibe therapy has an anti-
inflammatory effect. However, the results of individual studies on the effect of statin therapy …

Objective: To measure the efficacy of various types and dosages of statins on C-reactive
protein (CRP) levels in patients with dyslipidemia or coronary heart disease. Methods …

HMG-CoA reductase inhibitors (statins) are commonly used to manage dyslipidemia to
reduce cardiovascular disease (CVD) risk. High-sensitivity C-reactive protein (hs-CRP) is an …

Background: Metastatic uveal melanoma (MUM) is a highly aggressive, therapy-resistant
disease. Driver mutations in Gα-proteins GNAQ and GNA11 activate MAP-kinase and …

Objectives To estimate the prevalence of hypertriglyceridemia (HTG), determine the
association between HTG and the risk of ischemic heart disease and major adverse …