Meta-analysis of microsatellite instability in relation to clinicopathological characteristics and overall survival in gastric cancer

K Polom, L Marano, D Marrelli, R De Luca… - Journal of British …, 2018 - academic.oup.com
Background Several associations between microsatellite instability (MSI) and other
clinicopathological factors have been reported in gastric cancer, but the results have been …

[HTML][HTML] Carcinoma of the stomach: A review of epidemiology, pathogenesis, molecular genetics and chemoprevention

S Nagini - World journal of gastrointestinal oncology, 2012 - ncbi.nlm.nih.gov
Carcinoma of the stomach is still the second most common cause of cancer death
worldwide, although the incidence and mortality have fallen dramatically over the last 50 …

[HTML][HTML] Gastric cancer: Classification, histology and application of molecular pathology

B Hu, N El Hajj, S Sittler, N Lammert… - Journal of …, 2012 - ncbi.nlm.nih.gov
Gastric cancer remains one of the deadly diseases with poor prognosis. New classification
of gastric cancers based on histologic features, genotypes and molecular phenotypes helps …

Immunohistochemistry versus microsatellite instability testing in phenotyping colorectal tumors

NM Lindor, LJ Burgart, O Leontovich… - Journal of clinical …, 2002 - ascopubs.org
PURPOSE: To compare microsatellite instability (MSI) testing with immunohistochemical
(IHC) detection of hMLH1 and hMSH2 in colorectal cancer. PATIENTS AND METHODS …

Evaluation of tumor microsatellite instability using five quasimonomorphic mononucleotide repeats and pentaplex PCR

N Suraweera, A Duval, M Reperant, C Vaury, D Furlan… - Gastroenterology, 2002 - Elsevier
Background & Aims: The microsatellite instability (MSI) phenotype is a characteristic of the
hereditary nonpolyposis colorectal cancer syndrome as well as approximately 15% of …

Mutations at coding repeat sequences in mismatch repair-deficient human cancers: toward a new concept of target genes for instability

A Duval, R Hamelin - Cancer research, 2002 - AACR
Because the discovery of a link between mismatch repair deficiency and sporadic or
inherited human cancers characterized by microsatellite instability (MSI-H tumors), genes …

Development of a fluorescent multiplex assay for detection of MSI‐high tumors

JW Bacher, LA Flanagan, RL Smalley… - Disease …, 2004 - Wiley Online Library
Determining whether a tumor exhibits microsatellite instability (MSI) is useful in identifying
patients with hereditary non‐polyposis colorectal cancer and sporadic gastrointestinal …

Biomarkers for gastric cancer: prognostic, predictive or targets of therapy?

C Durães, GM Almeida, R Seruca, C Oliveira… - Virchows Archiv, 2014 - Springer
Gastric cancer is an aggressive disease often diagnosed at an advanced stage. Despite
improvements in surgical and adjuvant treatment approaches, gastric cancer remains a …

Multipopulation analysis of polymorphisms in five mononucleotide repeats used to determine the microsatellite instability status of human tumors

O Buhard, F Cattaneo, YF Wong, SF Yim… - Journal of clinical …, 2006 - ascopubs.org
Purpose Human gastrointestinal tumors with inactivated DNA mismatch repair system
(microsatellite instability [MSI] tumors) have distinct molecular and clinicopathologic profiles …

Diagnostic, predictive, prognostic, and therapeutic molecular biomarkers in third millennium: a breakthrough in gastric cancer

N Carlomagno, P Incollingo, V Tammaro… - BioMed research …, 2017 - Wiley Online Library
Introduction. Gastric cancer is the fifth most common cancer and the third cause of cancer
death. The clinical outcomes of the patients are still not encouraging with a low rate of 5 …