Immunomodulatory, anti-inflammatory, and anti-cancer properties of ginseng: a pharmacological update

JA Valdés-González, M Sánchez, I Moratilla-Rivera… - Molecules, 2023 - mdpi.com
Ginseng, a medicinal plant of the genus Panax, boasts a rich historical record of usage that
dates back to the Paleolithic period. This botanical is extensively acknowledged and …

Saponins derived from Gynostemma pentaphyllum regulate triglyceride and cholesterol metabolism and the mechanisms: A review

P Xie, HT Luo, WJ Pei, MY Xiao, FF Li, YL Gu… - Journal of …, 2023 - Elsevier
Abstract Ethnopharmacological relevance Gynostemma pentaphyllum (Thunb.) Makino (G.
pentaphyllum) can be used for both medicinal and tea and has lipid-lowering properties …

[HTML][HTML] The therapeutic effects of saikosaponins on depression through the modulation of neuroplasticity: From molecular mechanisms to potential clinical …

S Chen, K Wang, H Wang, Y Gao, K Nie, X Jiang… - Pharmacological …, 2024 - Elsevier
Depression is a major global health issue that urgently requires innovative and precise
treatment options. In this context, saikosaponin has emerged as a promising candidate …

An ethanolic extract of Arctium lappa L. leaves ameliorates experimental atherosclerosis by modulating lipid metabolism and inflammatory responses through PI3K/Akt …

H Guo, M Gong, Q Li, L Zhang, J Chen, J Chi… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Atherosclerosis (AS), a lipid-induced inflammatory
condition of the arteries, is a primary contributor to atherosclerotic cardiovascular diseases …

Effect of the Fermented Soy Q-CAN® Product on Biomarkers of Inflammation and Oxidation in Adults with Cardiovascular Risk, and Canonical Correlations between …

SM Jung, A Kaur, RI Amen, K Oda, S Rajaram… - Nutrients, 2023 - mdpi.com
Systemic low-grade inflammation plays a key role in the development of cardiovascular
disease (CVD) but the process may be modulated by consuming fermented soy foods. Here …

Anti-atherosclerosis mechanisms associated with regulation of non-coding RNAs by active monomers of traditional Chinese medicine

G Liu, L Tan, X Zhao, M Wang, Z Zhang… - Frontiers in …, 2023 - frontiersin.org
Atherosclerosis is the leading cause of numerous cardiovascular diseases with a high
mortality rate. Non-coding RNAs (ncRNAs), RNA molecules that do not encode proteins in …

Gypenoside induces apoptosis by inhibiting the PI3K/AKT/mTOR pathway and enhances T-cell antitumor immunity by inhibiting PD-L1 in gastric cancer

H Wu, W Lai, Q Wang, Q Zhou, R Zhang… - Frontiers in …, 2024 - frontiersin.org
Introduction: Gypenoside is a natural extract of Gynostemma pentaphyllum (Thunb.) Makino,
a plant in the Cucurbitaceae family. It has been reported to have antitumor effects on the …

Modulation of atherosclerosis‐related signaling pathways by Chinese herbal extracts: Recent evidence and perspectives

C Liu, X Guo, X Zhang - Phytotherapy Research, 2024 - Wiley Online Library
Atherosclerotic cardiovascular disease remains a preeminent cause of morbidity and
mortality globally. The onset of atherosclerosis underpins the emergence of ischemic …

Is the suppression of CD36 a promising way for atherosclerosis therapy?

SY Wen, X Zhi, HX Liu, X Wang, YY Chen… - Biochemical …, 2023 - Elsevier
Atherosclerosis is the main underlying pathology of many cardiovascular diseases and is
marked by plaque formation in the artery wall. It has posed a serious threat to the health of …

Antioxidant Profiling, Phytochemical Investigation and Pharmacognostic Evaluation of Nephrolepis biserrata (SW.) Schott (Nephrolepidaceae)

BO Oyawaluja, AA Oyawaluja, DE Akinyimika… - Tropical Journal of …, 2024 - tjpps.org
Natural product chemistry has contributed immensely to the discovery of bioactive
compounds and the development of pharmaceutical agents. In this study, the ethanol extract …