Background Polycystic ovary syndrome (PCOS) is the most common endocrinopathy among
reproductive age women. Although its cardinal manifestations include hyperandrogenism …

Brown adipose tissue (BAT) displays the unique capacity to generate heat through
uncoupled oxidative phosphorylation that makes it a very attractive therapeutic target for …

Adolescent polycystic ovary syndrome (PCOS) is a highly prevalent, reversible, endocrine-
metabolic mode essentially driven by ectopic fat, which, in turn, often results from a …

Insulin resistance is documented in clamp studies in 75% of women with polycystic ovary
syndrome (PCOS). Although it is not included in the diagnostic criteria of PCOS, there is a …

Oxidative stress (OS) is a condition that occurs as a result of an imbalance between the
production of reactive oxygen species (ROS) and the body's ability to detoxify and neutralize …

Excessive fat accumulation in the body causes overweight and obesity. To date, research
has confirmed that there are two types of adipose tissue with opposing functions: lipid …

In a healthy female reproductive system, a subtle hormonal and metabolic dance leads to
repetitive cyclic changes in the ovaries and uterus, which make an effective ovulation and …

Current concepts of polycystic ovary syndrome pathogenesis : Current Opinion in Pediatrics
Current concepts of polycystic ovary syndrome pathogenesis : Current Opinion in Pediatrics …

The gonadal steroids, including androgens, estrogens and progestogens, are involved in
the control of body fat distribution in humans. Nevertheless, not only the size and localization …

Objective To evaluate whether brown adipose tissue (BAT) activity is altered in women with
polycystic ovary syndrome (PCOS), and whether BAT activity correlates with plasma levels …