[HTML][HTML] Chemoresistance of cancer cells: requirements of tumor microenvironment-mimicking in vitro models in anti-cancer drug development
For decades, scientists have been using two-dimensional cell culture platforms for high-
throughput drug screening of anticancer drugs. Growing evidence indicates that the results …
throughput drug screening of anticancer drugs. Growing evidence indicates that the results …
Unravelling Surface Modification Strategies for Preventing Medical Device‐Induced Thrombosis
The use of biomaterials in implanted medical devices remains hampered by platelet
adhesion and blood coagulation. Thrombus formation is a prevalent cause of failure of these …
adhesion and blood coagulation. Thrombus formation is a prevalent cause of failure of these …
Graphene oxide containing chitosan scaffolds for cartilage tissue engineering
MA Shamekhi, H Mirzadeh, H Mahdavi… - International journal of …, 2019 - Elsevier
Enhancement of physical and mechanical properties of the scaffolds is achieved via various
methods including cross-linking and incorporation of nano particles. In the present research …
methods including cross-linking and incorporation of nano particles. In the present research …
[HTML][HTML] A nanoporous titanium surface promotes the maturation of focal adhesions and formation of filopodia with distinctive nanoscale protrusions by osteogenic …
While topography is a key determinant of the cellular response to biomaterials, the
mechanisms implicated in the cell-surface interactions are complex and still not fully …
mechanisms implicated in the cell-surface interactions are complex and still not fully …
Surface-engineered hybrid gelatin methacryloyl with nanoceria as reactive oxygen species responsive matrixes for bone therapeutics
Designing various transplantable biomaterials, especially nanoscale matrixes for bone
regeneration, involves precise tuning of topographical features. The cellular fate on such …
regeneration, involves precise tuning of topographical features. The cellular fate on such …
Ligand mobility-mediated cell adhesion and spreading
Cells live in a highly dynamic environment where their physical connection and
communication with the outside are achieved through receptor–ligands binding. Therefore …
communication with the outside are achieved through receptor–ligands binding. Therefore …
Optimizing surface properties of Ti13Nb13Zr alloy substrate for biomedical applications through modification with nano-alumina obtained by atomic layer deposition …
JD Uchoa, MV Santana, MVG Rodrigues… - Surface and Coatings …, 2023 - Elsevier
Abstract Ti13Nb13Zr (TNZ) alloys have attracted the interest of researchers as viable and
controllable alternatives for biometrics. The research on bioactive coatings of metal alloys …
controllable alternatives for biometrics. The research on bioactive coatings of metal alloys …
3-D printed Ti-6Al-4V scaffolds for supporting osteoblast and restricting bacterial functions without using drugs: Predictive equations and experiments
NJ Bassous, CL Jones, TJ Webster - Acta Biomaterialia, 2019 - Elsevier
Conditions resulting from musculoskeletal deficiencies (MSDs) are wide-ranging and retain
the likelihood for restricting motion or producing pain, especially in the lower back, neck, and …
the likelihood for restricting motion or producing pain, especially in the lower back, neck, and …
Nanostructure of bioactive glass affects bone cell attachment via protein restructuring upon adsorption
The nanostructure of engineered bioscaffolds has a profound impact on cell response, yet its
understanding remains incomplete as cells interact with a highly complex interfacial layer …
understanding remains incomplete as cells interact with a highly complex interfacial layer …
Simultaneous hydrothermal bioactivation with nano-topographic modulation of porous titanium alloys towards enhanced osteogenic and antimicrobial responses
Post-implantation failure associated with insufficient host tissue integration at the bone–
implant interface and aseptic loosening is a major concern in orthopaedics as well as in …
implant interface and aseptic loosening is a major concern in orthopaedics as well as in …