Poly (ethylene glycol) alternatives in biomedical applications

X Yao, C Qi, C Sun, F Huo, X Jiang - Nano Today, 2023 - Elsevier
Abstract Poly (ethylene glycol)(PEG) as gold standard has been extensively conjugated to
diagnostic and therapeutic agents or decorated on the surface of nanoplatforms, which is …

Drug Delivery Systems Based on Poly (2‐oxazoline) s and Poly (2‐oxazine) s

O Sedlacek, R Hoogenboom - Advanced Therapeutics, 2020 - Wiley Online Library
Abstract Poly (2‐oxazoline) s (PAOx) represent an established class of polymer materials
with a wide range of applications. In contrast, the homologous poly (2‐oxazine) s (PAOzi) …

Poly (2-oxazoline)-based stimulus-responsive (Co) polymers: An overview of their design, solution properties, surface-chemistries and applications

S Jana, M Uchman - Progress in Polymer Science, 2020 - Elsevier
Abstract Pseudopeptidic poly (2-oxazoline) s are a special class of bio-inspired polymers
with multiple applications, especially in the field of polymer therapeutics. Unsurprisingly …

Poly (2‐oxazoline) s: a comprehensive overview of polymer structures and their physical properties—an update

S Jana, R Hoogenboom - Polymer International, 2022 - Wiley Online Library
Abstract Poly (2‐alkyl/aryl‐2‐oxazoline) s (PAOxs) have gained immense attraction in the
polymer research community because of their relative ease of microwave‐assisted …

[HTML][HTML] Layer-by-layer cell encapsulation for drug delivery: the history, technique basis, and applications

W Li, X Lei, H Feng, B Li, J Kong, M Xing - Pharmaceutics, 2022 - mdpi.com
The encapsulation of cells with various polyelectrolytes through layer-by-layer (LbL) has
become a popular strategy in cellular function engineering. The technique sprang up in …

Poly (2-oxazoline)-protein conjugates

O Sedlacek, VR de la Rosa, R Hoogenboom - European Polymer Journal, 2019 - Elsevier
Abstract Poly (2-oxazoline) s (in literature abbreviated as PAOx, POx, or POZ, herein
referred to as PAOx) represent an emerging class of biocompatible polymers outperforming …

Poly (2-methyl-2-oxazoline) conjugates with doxorubicin: From synthesis of high drug loading water-soluble constructs to in vitro anti-cancer properties

O Sedlacek, A Van Driessche, A Uvyn… - Journal of controlled …, 2020 - Elsevier
Abstract Poly (2-oxazoline) s represent an emerging class of polymers with increasing
potential in biomedical sciences. To date, most of the work on poly (2-oxazoline)-drug …

Effect of polymer hydrophilicity and molar mass on the properties of the protein in protein–polymer conjugates: The case of PPEylated myoglobin

C Pelosi, C Duce, FR Wurm, MR Tinè - Biomacromolecules, 2021 - ACS Publications
Polyphosphoesters (PPEs), a versatile class of biodegradable and biocompatible polymers,
have been proposed as alternatives to poly (ethylene glycol)(PEG), which is suspected to be …

Synthesis and evaluation of methacrylated poly (2-ethyl-2-oxazoline) as a mucoadhesive polymer for nasal drug delivery

X Shan, S Aspinall, DB Kaldybekov… - ACS Applied Polymer …, 2021 - ACS Publications
Methacrylated poly (2-ethyl-2-oxazoline)(PEOZ) was synthesized by partial hydrolysis of 500
kDa PEOZ, and the resulting poly [(2-ethyl-2-oxazoline)-co-ethylenimine] P (EOZ-co-EI) was …

Polymer structure and property effects on solid dispersions with haloperidol: Poly (N-vinyl pyrrolidone) and poly (2-oxazolines) studies

X Shan, AC Williams, VV Khutoryanskiy - International Journal of …, 2020 - Elsevier
Abstract Poly (2-methyl-2-oxazoline)(PMOZ), poly (2-propyl-2-oxazoline)(PnPOZ) and poly
(2-isopropyl-2-oxazoline)(PiPOZ) were synthesized by hydrolysis of 50 kDa poly (2-ethyl-2 …