The use of small interfering RNAs (siRNAs) has been under investigation for the treatment of
several unmet medical needs, including acute lung injury/acute respiratory distress …

Messenger RNA (mRNA) is now in the limelight as a powerful tool for treating various
human diseases, especially malignant tumors, thanks to the remarkable clinical outcomes of …

RNA-based medicine is receiving growing attention for its diverse roles and potential
therapeutic capacity. The largest obstacle in its clinical translation remains identifying a safe …

Glioblastoma (GBM) is the most lethal form of brain tumor, being characterized by the rapid
growth and invasion of the surrounding tissue. The current standard treatment for …

An overview of the application of natural and synthetic, non-viral vectors for oligonucleotide
delivery into the lung is presented in this review, with a special focus on lung cancer. Due to …

Lung diseases are a leading cause of mortality worldwide and there exists urgent need for
new therapies. Approval of the first siRNA treatments in humans has opened the door for …

Published literature on cancer by health agencies and health organizations reveals
increased cancer incidence year by year. The first line of cancer treatment involves one or …

Breast cancer is the leading cause of cancer-related fatalities in female worldwide. Effective
therapies with low side effects for breast cancer treatment and prevention are, accordingly …

Neurodegeneration is hallmarked by the progressive loss of dopaminergic neurons and/or a
significant increase in protein aggregates in the brain. Neurodegenerative diseases are a …

Highlights•CPD is formed by thiolate-initiated ring-opening polymerization, which requires
three components: an initiator, a monomer and a terminator.•CPD can mediate thiol …