Deficits in trace fear memory and long-term potentiation in a mouse model for fragile X syndrome
Trace fear memory requires the activity of the anterior cingulate cortex (ACC) and is
sensitive to attention-distracting stimuli. Fragile X syndrome is the most common form of …
sensitive to attention-distracting stimuli. Fragile X syndrome is the most common form of …
Inhibition of p21-activated kinase rescues symptoms of fragile X syndrome in mice
Fragile X syndrome (FXS), the most commonly inherited form of mental retardation and
autism, is caused by transcriptional silencing of the fragile X mental retardation 1 (FMR1) …
autism, is caused by transcriptional silencing of the fragile X mental retardation 1 (FMR1) …
Emotion and consciousness
N Tsuchiya, R Adolphs - Trends in cognitive sciences, 2007 - cell.com
Consciousness and emotion feature prominently in our personal lives, yet remain enigmatic.
Recent advances prompt further distinctions that should provide more experimental traction …
Recent advances prompt further distinctions that should provide more experimental traction …
Psychological risk factors in headache: CME
Headache is a chronic disease that occurs with varying frequency and results in varying
levels of disability. To date, the majority of research and clinical focus has been on the role …
levels of disability. To date, the majority of research and clinical focus has been on the role …
[HTML][HTML] The cholinergic basal forebrain links auditory stimuli with delayed reinforcement to support learning
Animals learn to fear conditioned sound stimuli (CSs) that accompany aversive
unconditioned stimuli (USs). Auditory cortex (ACx) circuits reorganize to support auditory …
unconditioned stimuli (USs). Auditory cortex (ACx) circuits reorganize to support auditory …
[HTML][HTML] Role of anterior cingulate cortex inputs to periaqueductal gray for pain avoidance
JY Lee, T You, CH Lee, GH Im, H Seo, CW Woo… - Current Biology, 2022 - cell.com
Although pain-related excessive fear is known to be a key factor in chronic pain disability,
which involves the anterior cingulate cortex (ACC), little is known about the downstream …
which involves the anterior cingulate cortex (ACC), little is known about the downstream …
Enhanced presynaptic neurotransmitter release in the anterior cingulate cortex of mice with chronic pain
The anterior cingulate cortex (ACC) is a forebrain structure known for its roles in learning
and memory. Recent studies show that painful stimuli activate the prefrontal cortex and that …
and memory. Recent studies show that painful stimuli activate the prefrontal cortex and that …
[HTML][HTML] Thalamus and claustrum control parallel layer 1 circuits in retrosplenial cortex
EKW Brennan, I Jedrasiak-Cape, S Kailasa, SP Rice… - Elife, 2021 - elifesciences.org
The granular retrosplenial cortex (RSG) is critical for both spatial and non-spatial behaviors,
but the underlying neural codes remain poorly understood. Here, we use optogenetic circuit …
but the underlying neural codes remain poorly understood. Here, we use optogenetic circuit …
Effects of elevation of brain magnesium on fear conditioning, fear extinction, and synaptic plasticity in the infralimbic prefrontal cortex and lateral amygdala
N Abumaria, B Yin, L Zhang, XY Li, T Chen… - Journal of …, 2011 - Soc Neuroscience
Anxiety disorders, such as phobias and posttraumatic stress disorder, are among the most
common mental disorders. Cognitive therapy helps in treating these disorders; however …
common mental disorders. Cognitive therapy helps in treating these disorders; however …
Fear acquisition requires awareness in trace but not delay conditioning
The present study explored fear acquisition in differential delay versus trace conditioning in
regard to the potential role of the acquired contingency awareness. One of two neutral …
regard to the potential role of the acquired contingency awareness. One of two neutral …