Mechanisms of oxidative stress in metabolic syndrome
SK Masenga, LS Kabwe, M Chakulya… - International journal of …, 2023 - mdpi.com
Metabolic syndrome is a cluster of conditions associated with the risk of diabetes mellitus
type 2 and cardiovascular diseases (CVDs). Metabolic syndrome is closely related to …
type 2 and cardiovascular diseases (CVDs). Metabolic syndrome is closely related to …
The FOXO family of transcription factors: key molecular players in gastric cancer
Y Liu, X Ao, Y Jia, X Li, Y Wang, J Wang - Journal of Molecular Medicine, 2022 - Springer
Gastric cancer (GC) is the fifth most frequently diagnosed cancer worldwide and the third
leading cause of cancer-related death with an oncological origin. Despite its decline in …
leading cause of cancer-related death with an oncological origin. Despite its decline in …
Multi-omics of human plasma reveals molecular features of dysregulated inflammation and accelerated aging in schizophrenia
A Campeau, RH Mills, T Stevens, LA Rossitto… - Molecular …, 2022 - nature.com
Schizophrenia is a devastating psychiatric illness that detrimentally affects a significant
portion of the worldwide population. Aging of schizophrenia patients is associated with …
portion of the worldwide population. Aging of schizophrenia patients is associated with …
[HTML][HTML] An overview of glycosylation and its impact on cardiovascular health and disease
KJ Loaeza-Reyes, E Zenteno… - Frontiers in molecular …, 2021 - frontiersin.org
The cardiovascular system is a complex and well-organized system in which glycosylation
plays a vital role. The heart and vascular wall cells are constituted by an array of specific …
plays a vital role. The heart and vascular wall cells are constituted by an array of specific …
Roles of protein post-translational modifications in glucose and lipid metabolism: mechanisms and perspectives
The metabolism of glucose and lipids is essential for energy production in the body, and
dysregulation of the metabolic pathways of these molecules is implicated in various acute …
dysregulation of the metabolic pathways of these molecules is implicated in various acute …
Mannose receptor deficiency impacts bone marrow and circulating immune cells during high fat diet induced obesity
The mannose receptor C-type 1 (Mrc1) is a C-type lectin receptor expressed on the immune
cells and sinusoidal endothelial cells (ECs) of several tissues, including the bone marrow …
cells and sinusoidal endothelial cells (ECs) of several tissues, including the bone marrow …
Impact of asialoglycoprotein receptor and mannose receptor deficiency on murine plasma N-glycome profiles
The asialoglycoprotein receptor (ASGPR) and the mannose receptor C-type 1 (MRC1) are
well known for their selective recognition and clearance of circulating glycoproteins …
well known for their selective recognition and clearance of circulating glycoproteins …
[HTML][HTML] The role of protein glycosylation in the occurrence and outcome of acute ischemic stroke
J Li, Y Qiu, C Zhang, H Wang, R Bi, Y Wei, Y Li… - Pharmacological …, 2023 - Elsevier
Acute ischemic stroke (AIS) is a serious and life-threatening disease worldwide. Despite
thrombolysis or endovascular thrombectomy, a sizeable fraction of patients with AIS have …
thrombolysis or endovascular thrombectomy, a sizeable fraction of patients with AIS have …
Exploring apolipoprotein C-III: pathophysiological and pharmacological relevance
CJ Packard, A Pirillo, S Tsimikas… - Cardiovascular …, 2023 - academic.oup.com
The availability of pharmacological approaches able to effectively reduce circulating LDL
cholesterol (LDL-C) has led to a substantial reduction in the risk of atherosclerosis-related …
cholesterol (LDL-C) has led to a substantial reduction in the risk of atherosclerosis-related …
FoxO3 and oxidative stress: a multifaceted role in cellular adaptation
VS Bernardo, FF Torres, DGH Da Silva - Journal of Molecular Medicine, 2023 - Springer
Oxidative stress is a major cause of morbidity and mortality in human health and disease. In
this review, we focus on the Forkhead Box (Fox) subclass O3 (FoxO3), an extensively …
this review, we focus on the Forkhead Box (Fox) subclass O3 (FoxO3), an extensively …