Transcription regulation in archaea
AM Gehring, JE Walker, TJ Santangelo - Journal of bacteriology, 2016 - Am Soc Microbiol
The known diversity of metabolic strategies and physiological adaptations of archaeal
species to extreme environments is extraordinary. Accurate and responsive mechanisms to …
species to extreme environments is extraordinary. Accurate and responsive mechanisms to …
The innate immune factor RPRD2/REAF and its role in the Lv2 restriction of HIV
KA Jackson-Jones, Á McKnight, RD Sloan - Mbio, 2023 - Am Soc Microbiol
Intracellular innate immunity involves co-evolved antiviral restriction factors that specifically
inhibit infecting viruses. Studying these restrictions has increased our understanding of viral …
inhibit infecting viruses. Studying these restrictions has increased our understanding of viral …
Nutrient-dependent control of RNA polymerase II elongation rate regulates specific gene expression programs by alternative polyadenylation
C Yague-Sanz, Y Vanrobaeys… - Genes & …, 2020 - genesdev.cshlp.org
Transcription by RNA polymerase II (RNAPII) is a dynamic process with frequent variations
in the elongation rate. However, the physiological relevance of variations in RNAPII …
in the elongation rate. However, the physiological relevance of variations in RNAPII …
The Nrd1-like protein Seb1 coordinates cotranscriptional 3′ end processing and polyadenylation site selection
JF Lemay, S Marguerat, M Larochelle… - Genes & …, 2016 - genesdev.cshlp.org
Termination of RNA polymerase II (RNAPII) transcription is associated with RNA 3′ end
formation. For coding genes, termination is initiated by the cleavage/polyadenylation …
formation. For coding genes, termination is initiated by the cleavage/polyadenylation …
Coupling of PARP1-mediated chromatin structural changes to transcriptional RNA polymerase II elongation and cotranscriptional splicing
EA Matveeva, QMH Al-Tinawi, EC Rouchka… - Epigenetics & …, 2019 - Springer
Background Recently, we showed that PARP1 is involved in cotranscriptional splicing,
possibly by bridging chromatin to RNA and recruiting splicing factors. It also can influence …
possibly by bridging chromatin to RNA and recruiting splicing factors. It also can influence …
A generative model for the behavior of RNA polymerase
JG Azofeifa, RD Dowell - Bioinformatics, 2017 - academic.oup.com
Motivation Transcription by RNA polymerase is a highly dynamic process involving multiple
distinct points of regulation. Nascent transcription assays are a relatively new set of high …
distinct points of regulation. Nascent transcription assays are a relatively new set of high …
The association of the RSC remodeler complex with chromatin is influenced by the prefoldin-like Bud27 and determines nucleosome positioning and polyadenylation …
A Cuevas-Bermúdez, V Martínez-Fernández… - … et Biophysica Acta (BBA …, 2024 - Elsevier
The tripartite interaction between the chromatin remodeler complex RSC, RNA polymerase
subunit Rpb5 and prefoldin-like Bud27 is necessary for proper RNA pol II elongation. Indeed …
subunit Rpb5 and prefoldin-like Bud27 is necessary for proper RNA pol II elongation. Indeed …
The CDK7 inhibitor THZ1 alters RNA polymerase dynamics at the 5′ and 3′ ends of genes
Abstract The t (8; 21) is one of the most frequent chromosomal translocations associated
with acute myeloid leukemia (AML). We found that t (8; 21) AML were extremely sensitive to …
with acute myeloid leukemia (AML). We found that t (8; 21) AML were extremely sensitive to …
Control of gene expression in senescence through transcriptional read-through of convergent protein-coding genes
L Muniz, MK Deb, M Aguirrebengoa, S Lazorthes… - Cell reports, 2017 - cell.com
Antisense RNAs are non-coding RNAs that can regulate their corresponding sense RNAs
and are generally produced from specific promoters. We uncover here a family of antisense …
and are generally produced from specific promoters. We uncover here a family of antisense …
Versatile approach for functional analysis of human proteins and efficient stable cell line generation using FLP-mediated recombination system
RJ Szczesny, K Kowalska, K Klosowska-Kosicka… - PloS one, 2018 - journals.plos.org
Deciphering a function of a given protein requires investigating various biological aspects.
Usually, the protein of interest is expressed with a fusion tag that aids or allows subsequent …
Usually, the protein of interest is expressed with a fusion tag that aids or allows subsequent …