Devices, systems and methods are described herein to provide improved steerability for
delivering a prosthesis to a body location, for example, for delivering a replacement mitral …

(57) ABSTRACT A prosthesis can be configured to grasp intralumenal tissue when deployed
within a body cavity and prevent axial flow of fluid around an exterior of the prosthesis. The …

A prosthesis can comprise an expandable frame, a plurality of distal anchors and a plurality
of proximal anchors. The anchors can extend outwardly from the frame. The frame can be …

Methods are described herein for delivering a replacement mitral valve to a native mitral
valve location. In one method, ventricular anchors of the replacement mitral valve are …

Transcatheter therapies for the treatment of valve heart diseases have expanded
dramatically over the last years. The new developments and improvements in devices and …

A replacement heart valve can have an expandable frame configured to engage a native
valve annulus. A valve body can be mounted onto the expandable frame to provide …

A mitral valve prosthesis includes an hourglass shaped inner frame and a bulbous outer
frame. A valve body having a plurality of leaflets is positioned within an interior region of the …

A replacement heart valve can have an expandable frame configured to engage a native
valve annulus. A valve body can be mounted onto the expandable frame to provide …

The clip is introduced through a 24F sheath from the right femoral vein into the left atrium via
a transseptal puncture. It is then guided using a series of turning knobs and …

A replacement mitral valve prosthesis includes a support structure and a valve body having
three flexible leaflets. The support structure preferably includes an internal valve frame and …