Colorectal cancer has served as a genetic and biological paradigm for the evolution of solid
tumors, and these insights have illuminated early detection, risk stratification, prevention …

The intestinal microbiota, composed of a large population of microorganisms, is often
considered a “forgotten organ” in human health and diseases. Increasing evidence indicates …

An increasing number of studies have revealed that the progression of colorectal cancer
(CRC) is related to gut microbiome composition. Under normal conditions, the gut …

The gut microbiota acts as a real organ. The symbiotic interactions between resident micro-
organisms and the digestive tract highly contribute to maintain the gut homeostasis …

Inflammation is emerging as one of the hallmarks of cancer, yet its role in most tumors
remains unclear. Whereas a minority of solid tumors are associated with overt inflammation …

Colorectal cancer, the fourth leading cause of cancer-related death worldwide, is a
multifactorial disease involving genetic, environmental and lifestyle risk factors. In addition …

The gut of warm-blooded animals is colonized by microbes possibly constituting at least 100
times more genetic material of microbial cells than that of the somatic cells of the host. These …

Colorectal cancer (CRC) presents a considerable disease burden worldwide. The human
colon is also an anatomical location with the largest number of microbes. It is natural …

Colorectal cancer (CRC) is one of the most common cancers worldwide. As with other
cancers, CRC is a multifactorial disease due to the combined effect of genetic and …

Background & Aims Colorectal cancer (CRC) development has been associated with
increased proportions of Bacteroides fragilis and certain Streptococcus, Fusobacterium, and …