The adequate availability and metabolism of three essential trace elements, iodine,
selenium and iron, provide the basic requirements for the function and action of the thyroid …

The ability of the body to maintain homeostasis requires constant communication between
the brain and peripheral tissues. Different organs produce signals, often in the form of …

In the past two decades significant progress has been made in uncovering the biological
function of selenium. Selenium, an essential trace element, is required for the biogenesis of …

Selenium (Se) is a naturally occurring essential micronutrient that is required for human
health. The existing form of Se includes inorganic and organic. In contrast to the inorganic …

α-lipoic acid (LA) is an essential cofactor for mitochondrial dehydrogenases and is required
for cell growth, metabolic fuel production, and antioxidant defense. In vitro, LA binds copper …

Actin and its dynamic structural remodelings are involved in multiple cellular functions,
including maintaining cell shape and integrity, cytokinesis, motility, navigation, and muscle …

Selenocysteine is a catalytic residue at the active site of all selenoenzymes in bacteria and
mammals, and it is incorporated into the polypeptide backbone by a co-translational process …

Background Low selenium concentrations are associated with worse outcomes in heart
failure (HF). However, the underlying pathophysiologic mechanisms remain incompletely …

Selenium has been proven to influence several biological functions, showing to be an
essential micronutrient. The functional studies demonstrated the benefits of a balanced …

Selenium (Se) is an essential trace element, which is inserted as selenocysteine (Sec) into
selenoproteins during biosynthesis, orchestrating their expression and activity. Se is …